Chantarojanasiri Tanyaporn, Ratanavaraporn Juthamas, Keeratihattayakorn Saran
Department of Internal medicine, Rajavithi Hospital, College of Medicine Rangsit University, Bangkok, Thailand.
Biomedical Engineering Program, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.
Clin Endosc. 2025 Jul;58(4):586-594. doi: 10.5946/ce.2024.252. Epub 2025 Apr 28.
The mechanical properties of biodegradable stent when fabricated using different number of pins per row of fabrication has been limited. We compared the radial compressive force of polydioxanone (PDO) stent that was fabricated in hook and cross manner, using 13, 17 and 19 pins per row and measure the radial compressive force and ex vivo deployment.
The PDO stents fabricated by the in-house aluminum mandrel were tested for radial force using plate compression until the stent achieved 50% strain. The relationship between compression force and %strain was calculated. Ex vivo testing of stent expansion against short segment stricture was performed in a pig small intestine compared between PDO hook cross PDO stent and braided metallic stent.
The stent shortening of 16.40%, 31.20% and 19.24% was observed in 13-, 17- and 19-pin-per-row, respectively. The maximum force to achieve 50% strain were 0.503, 1.168 and 1.008 N for 13, 17 and 19 pins per row, respectively. The stent fabricated using hook and cross pattern demonstrated higher conformability to anatomical stricture when compared with braided stent.
PDO stent fabricated using 17 pins per row demonstrated highest radial force when compared with 13 and 19 pins per row.
使用每行不同数量的销钉制造的可生物降解支架的机械性能有限。我们比较了以钩形和十字形制造的聚对二氧环己酮（PDO）支架的径向压缩力，每行使用13、17和19个销钉，并测量径向压缩力和体外展开情况。
使用内部铝芯轴制造的PDO支架通过平板压缩测试径向力，直到支架达到50%应变。计算压缩力与应变百分比之间的关系。在猪小肠中对PDO钩形十字形PDO支架和编织金属支架进行了针对短节段狭窄的支架扩张体外测试。
每行13个、17个和19个销钉的支架缩短率分别为16.40%、31.20%和19.24%。每行13个、17个和19个销钉达到50%应变时的最大力分别为0.503 N、1.168 N和1.008 N。与编织支架相比，采用钩形和十字形图案制造的支架对解剖学狭窄的顺应性更高。
与每行13个和19个销钉相比，每行使用17个销钉制造的PDO支架表现出最高的径向力。
