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不可切除食管癌患者自膨式金属支架置入术疗效比较

Comparison of Efficacy of Self-Expandable Metallic Stent Placement in the Unresectable Esophageal Cancer Patients.

作者信息

Uesato Masaya, Akutsu Yasunori, Murakami Kentarou, Muto Yorihiko, Kagaya Akiko, Nakano Akira, Aikawa Mizuho, Tamachi Tomohide, Arasawa Takahiro, Amagai Hiroyuki, Muto Yasuhide, Matsubara Hisahiro

机构信息

Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba-shi, Chiba 260-8670, Japan.

出版信息

Gastroenterol Res Pract. 2017;2017:2560510. doi: 10.1155/2017/2560510. Epub 2017 Jul 27.

Abstract

This is a retrospective study to evaluate the prevention of complications of metallic stent placement in patients with unresectable advanced esophageal cancer. A total of 87 patients were treated with 4 types of metal stents in the esophagus over a period of 18 years. Stent placement was technically successful. The most common prior treatment was chemoradiotherapy. There were no significant differences in the rate of patients with no complications among the prior treatments. Approximately, 30% of patients had the most common chest pain in complications. Stent placement within one month after the completion of chemoradiotherapy should be avoided for the prevention of the chest pain. There was no significant difference in the rate of patients with no complications by lesion location. The rate of no complications was higher for the Niti-S stent than the Gianturco Z-stent or Ultraflex stent. Of note, no complications were noted for the Niti-S ultrathin stent at all. Among cases of stent-related death, the most common type of complication was respiratory disorder caused by the stent that seems to be thick and hard. Therefore, the stent with thin and flexible characteristics like the Niti-S ultrathin stent will solve the various problems of esophageal stent placement.

摘要

这是一项回顾性研究,旨在评估不可切除的晚期食管癌患者金属支架置入并发症的预防情况。在18年的时间里,共有87例患者在食管中接受了4种类型的金属支架治疗。支架置入在技术上是成功的。最常见的先前治疗是放化疗。先前治疗中无并发症患者的比例没有显著差异。大约30%的患者在并发症中出现最常见的胸痛。为预防胸痛,应避免在放化疗完成后1个月内进行支架置入。按病变部位划分,无并发症患者的比例没有显著差异。Niti-S支架无并发症的比例高于Gianturco Z支架或Ultraflex支架。值得注意的是,Niti-S超薄支架完全没有出现并发症。在与支架相关的死亡病例中,最常见的并发症类型是由似乎厚且硬的支架引起的呼吸障碍。因此,具有薄且柔韧特性的支架,如Niti-S超薄支架,将解决食管支架置入的各种问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08e4/5551542/5218f37dee89/GRP2017-2560510.001.jpg

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