Mayer U, Buhl N, Sachs H, Sigel H
Dtsch Med Wochenschr. 1985 Aug 23;110(34):1293-6. doi: 10.1055/s-2008-1068999.
A 60-year-old woman swallowed 2.4 g verapamil in a retard form (Isoptin retard). Depsite intensive efforts she died 44 hours later in a coma due to circulatory collapse. In contrast to other reported cases of poisoning, the verapamil concentration in plasma continued to rise. This atypical course with continuing absorption of verapamil was due to small-intestinal deposits of the drug, found at autopsy.
一名60岁女性吞服了2.4克缓释型维拉帕米（异搏定缓释片）。尽管进行了积极抢救，她仍在44小时后因循环衰竭陷入昏迷并死亡。与其他报道的中毒病例不同，其血浆中维拉帕米浓度持续上升。这种维拉帕米持续吸收的非典型病程是由于尸检时发现的小肠药物沉积所致。
