Early Time-Restricted Eating Improves Weight Loss While Preserving Muscle: An 8-Week Trial in Young Women.

: Time-restricted eating (TRE) has gained attention as a novel dietary intervention that restricts the daily eating window, potentially offering improved metabolic health and body composition. Nevertheless, whether early TRE (eTRE) or delayed TRE (dTRE) best enhances resistance training (RT) adaptations remains unclear. : In this 8-week randomized study, 24 healthy young women with limited RT experience were assigned into one of three groups: eTRE (an 8:00 AM-2:00 PM feeding window), dTRE (12:00 PM-6:00 PM), or the control (8:00 AM-8:00 PM). Apart from the timing restrictions, no further dietary guidance was provided. All of the participants performed standardized knee-supported push-ups (4 sets × 10 reps, three sessions/week). The primary outcomes included body weight, the thickness of the triceps brachii long head (measured via ultrasound), and push-up endurance. : The eTRE group achieved a significant reduction in body weight (-2.61 ± 1.06 kg; < 0.001), which surpassed the changes observed in both the dTRE (-1.44 ± 1.12 kg) and control (-0.48 ± 0.64 kg) groups. However, no significant between-group differences emerged for muscle thickness or push-up performance. All groups showed comparable improvements in triceps brachii thickness (a 1.36-1.55 mm increase) and push-up endurance (62-74 additional repetitions). : Early TRE (8:00 AM-2:00 PM) appears to be more beneficial than delayed TRE (12:00 PM-6:00 PM) for weight management when combined with RT, yet both TRE regimens result in similar improvements in muscle thickness and endurance. These findings suggest that optimizing meal timing in alignment with circadian rhythms may enhance weight control without hindering muscle adaptations, providing a practical approach for individuals seeking to lose weight while preserving or increasing their muscular fitness. Future research involving larger samples and diverse populations is warranted to confirm these results and clarify the underlying metabolic mechanisms.