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双曲线极化激元耦合发射光学显微镜

Hyperbolic polariton-coupled emission optical microscopy.

作者信息

Li Shilong, Liu Zhaowei, Lee Yeon Ui

机构信息

Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou, China.

Department of Electrical and Computer Engineering, University of California, San Diego, USA.

出版信息

Nanophotonics. 2025 Jan 28;14(8):1213-1219. doi: 10.1515/nanoph-2024-0617. eCollection 2025 Apr.

Abstract

A new type of optical microscopy based on hyperbolic polariton-coupled emission (HPCE) is demonstrated. By employing hyperbolic metamaterials as the substrate, we show a nearly 6-fold increase in fluorescence intensity in the HPCE microscope compared to total internal reflection fluorescence (TIRF) on glass substrates. Moreover, we achieve precise, time-dependent control of the fluorescence intensity by modulating the incidence angle with a galvo scanner. This tunability offers extensive potential for applications in super-resolution fluorescence microscopy and high-sensitivity sensing, enabling real-time fluorescence intensity adjustment.

摘要

展示了一种基于双曲线极化激元耦合发射(HPCE)的新型光学显微镜。通过使用双曲线超材料作为基底,我们发现与玻璃基底上的全内反射荧光(TIRF)相比,HPCE显微镜中的荧光强度增加了近6倍。此外,我们通过使用振镜扫描仪调制入射角来实现对荧光强度的精确、随时间变化的控制。这种可调性为超分辨率荧光显微镜和高灵敏度传感应用提供了广泛的潜力,能够进行实时荧光强度调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6f0/12019955/29de3758a5cd/j_nanoph-2024-0617_fig_001.jpg

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