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纳米材料在肝细胞癌经动脉化疗栓塞治疗中的现状与最新进展

Current status and recent progress of nanomaterials in transcatheter arterial chemoembolization therapy for hepatocellular carcinoma.

作者信息

Sun Jia, Li Hai-Liang, Zhou Wen-Jun, Ma Zeng-Xin, Huang Xiao-Pei, Li Cheng

机构信息

Department of Hepatobiliary Pancreatic Hernia Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou 510317, Guangdong Province, China.

出版信息

World J Clin Oncol. 2025 Apr 24;16(4):104435. doi: 10.5306/wjco.v16.i4.104435.

Abstract

Hepatocellular carcinoma (HCC) remains one of the most common cancers worldwide. Transcatheter arterial chemoembolization has become a common treatment modality for some patients with unresectable advanced HCC. Since the introduction of nanomaterials in 1974, their use in various fields has evolved rapidly. In medical applications, nanomaterials can serve as carriers for the delivery of chemotherapeutic drugs to tumour tissues. Additionally, nanomaterials have potential for tumour imaging. This article covers the properties and uses of several kinds of nanomaterials, focusing on their use in transcatheter arterial chemoembolization for HCC treatment. This paper also discusses the limitations currently associated with the use of nanomaterials.

摘要

肝细胞癌(HCC)仍然是全球最常见的癌症之一。经动脉化疗栓塞术已成为一些无法切除的晚期HCC患者的常用治疗方式。自1974年引入纳米材料以来,它们在各个领域的应用迅速发展。在医学应用中,纳米材料可作为将化疗药物递送至肿瘤组织的载体。此外,纳米材料具有肿瘤成像的潜力。本文涵盖了几种纳米材料的特性和用途,重点介绍了它们在经动脉化疗栓塞术治疗HCC中的应用。本文还讨论了目前与纳米材料使用相关的局限性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0557/12019268/1c2c08188b66/104435-g001.jpg

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