Chabrol H, Guell A, Moron P
Encephale. 1985 May-Jun;11(3):121-3.
Regional cerebral blood flow (r CBF) was compared in ten adolescents with hebephrenia who were never treated with neuroleptics and ten normal controls using the Xenon 133 inhalation method. There were no differences in mean hemispheric blood flow. The main difference was the loss of the "hyperfrontal pattern" in the schizophrenics: the prefrontal values were only 0.7% greater than the blood flow in the rest of the hemisphere, compared with 14.6% in the controls.
使用氙133吸入法,对10名从未接受过抗精神病药物治疗的青春期精神分裂症患者和10名正常对照者的局部脑血流量(r CBF)进行了比较。半球平均血流量没有差异。主要差异在于精神分裂症患者失去了“额叶优势模式”:前额叶的值仅比半球其他部位的血流量高0.7%,而对照组为14.6%。