Rodriguez Alejandro A, Vedantam Shyam, Acosta Camilo J, Bhalla Sean, Barkin Jodie A
Department of Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL.
Division of Digestive Health and Liver Diseases, Leonard M. Miller School of Medicine, University of Miami, Miami, FL.
ACG Case Rep J. 2025 Apr 25;12(5):e01674. doi: 10.14309/crj.0000000000001674. eCollection 2025 May.
Metastases in pancreatic ductal adenocarcinoma are present in over 50% of cases at the time of diagnosis, with the liver, peritoneum, and lung being some of the most common sites. By contrast, solitary distant metastasis to the colon is a rare entity but clinically significant. We report 2 cases of synchronous pancreatic ductal adenocarcinoma distant metastasis to colon along with a literature review. Our cases demonstrate the utility of colonoscopy to diagnose metastatic disease. Last, as highlighted, palliative stenting can be used in cases of complete obstruction. : pancreatic cancer; metastasis; obstruction; malignant large bowel obstruction; colonoscopy.
胰腺导管腺癌在诊断时超过50%的病例存在转移,肝脏、腹膜和肺是一些最常见的转移部位。相比之下,孤立性远处转移至结肠是一种罕见但具有临床意义的情况。我们报告2例同步发生的胰腺导管腺癌远处转移至结肠的病例,并进行文献复习。我们的病例证明了结肠镜检查在诊断转移性疾病中的作用。最后,如所强调的,在完全梗阻的病例中可使用姑息性支架置入术。:胰腺癌;转移;梗阻;恶性大肠梗阻;结肠镜检查