Yu Xue-Lu, Peng Jian-Hui, Chang Qing, Chen Jing-Wen, Yang Ji-Shun, Wang Ming-Ke
Naval Medical Center of People's Liberation Army, Naval Medical University, Shanghai 200052, China.
Department of Quality Management, Guangdong Second Provincial General Hospital, Guangzhou 510317, Guangdong Province, China.
World J Gastrointest Surg. 2025 Apr 27;17(4):102144. doi: 10.4240/wjgs.v17.i4.102144.
In this article, we have addressed the recent published article by Wang which examines risk factors associated with surgical site infections (SSIs) and evaluates the effectiveness of prophylactic antibiotics in their prevention. Wang identified several significant risk factors of SSIs, including age ≥ 60 years, diabetes mellitus, and surgical complications such as insufficient cystic duct stump closure, gallbladder perforation, empyema, and postoperative hematoma. Their findings suggest that prophylactic antibiotics can serve as a protective factor against SSIs. However, other reported risk factors and preventive strategies warrant consideration to further reduce the incidence of SSIs, lower healthcare costs, and enhance patient outcomes. Additionally, the judicious use of prophylactic antibiotics is crucial in light of the growing global challenge of antibiotic resistance caused by the misuse and overuse of antibiotics. Effective management strategies for prophylactic antibiotic use should be prioritized to balance infection control with the need to combat antimicrobial resistance.
在本文中，我们探讨了王最近发表的一篇文章，该文章研究了与手术部位感染（SSIs）相关的风险因素，并评估了预防性抗生素在预防手术部位感染中的有效性。王确定了手术部位感染的几个重要风险因素，包括年龄≥60岁、糖尿病以及手术并发症，如胆囊管残端闭合不全、胆囊穿孔、积脓和术后血肿。他们的研究结果表明，预防性抗生素可作为预防手术部位感染的保护因素。然而，其他已报道的风险因素和预防策略值得考虑，以进一步降低手术部位感染的发生率、降低医疗成本并改善患者预后。此外，鉴于抗生素滥用和过度使用导致的全球抗生素耐药性挑战日益严峻，谨慎使用预防性抗生素至关重要。应优先制定预防性抗生素使用的有效管理策略，以在控制感染与应对抗菌药物耐药性需求之间取得平衡。
