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手术后颈髓病所致迟发性脊髓白质综合征的影像学改变:一例报告并文献复习

Radiographic changes in delayed white cord syndrome from postsurgical cervical myelopathy: A case report and review of the literature.

作者信息

Sheen Serena, Sheen Volney

机构信息

Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115, USA.

出版信息

Radiol Case Rep. 2025 Apr 12;20(7):3231-3235. doi: 10.1016/j.radcr.2025.03.062. eCollection 2025 Jul.

DOI:10.1016/j.radcr.2025.03.062
PMID:40292155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12018174/
Abstract

White cord syndrome (WCS), also referred to as reperfusion injury of the spinal cord, is a rare condition involving sudden neurological deterioration following cervical spinal decompression. The syndrome is diagnosed in the absence of an iatrogenic cord injury or perioperative complications. Both loss of neurophysiological signaling during intraoperative monitoring and the appearance of hyper-intensity on T2-weighted magnetic resonance imaging are hallmarks of WCS. We present a report of a female patient who presented with the condition and followed her imaging studies longitudinally. Imaging studies showed prolonged and persistent contrast enhancement over a year and a half postsurgery. Such findings have not previously been reported with WCS. We provide a brief review of the literature, highlighting the main radiologic findings.

摘要

白脊髓综合征(WCS),也被称为脊髓再灌注损伤,是一种罕见的病症,涉及颈椎减压术后突然出现的神经功能恶化。该综合征在不存在医源性脊髓损伤或围手术期并发症的情况下被诊断出来。术中监测期间神经生理信号的丧失以及T2加权磁共振成像上高强度信号的出现都是WCS的特征。我们报告了一名患有该病症的女性患者,并对其影像学研究进行了纵向跟踪。影像学研究显示,术后一年半以上出现了持续且持久的对比增强。此前尚未有WCS出现此类发现的报道。我们对文献进行了简要综述,突出了主要的放射学发现。

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本文引用的文献

1
Delayed-onset white cord syndrome after anterior and posterior cervical decompression surgery for symptomatic ossification of spinal ligaments: illustrative cases.因症状性脊柱韧带骨化行颈椎前后路减压手术后的迟发性白质脊髓综合征:病例展示
J Neurosurg Case Lessons. 2021 May 10;1(19):CASE2113. doi: 10.3171/CASE2113.
2
Utility of MRI Enhancement Pattern in Myelopathies With Longitudinally Extensive T2 Lesions.磁共振成像强化模式在伴有纵向广泛T2高信号病变的脊髓病中的应用价值
Neurol Clin Pract. 2021 Oct;11(5):e601-e611. doi: 10.1212/CPJ.0000000000001036.
3
White Cord Syndrome Causing Transient Tetraplegia After Posterior Decompression and Fusion.
后路减压融合术后导致短暂性四肢瘫痪的白索综合征
Ochsner J. 2020 Fall;20(3):334-338. doi: 10.31486/toj.19.0081.
4
White cord syndrome in a pediatric patient: A case report and review.一名儿科患者的白索综合征:病例报告与文献复习
Radiol Case Rep. 2020 Sep 15;15(11):2343-2347. doi: 10.1016/j.radcr.2020.08.047. eCollection 2020 Nov.
5
"White Cord Syndrome" of Acute Hemiparesis After Posterior Cervical Decompression and Fusion for Chronic Cervical Stenosis.慢性颈椎管狭窄后路颈椎减压融合术后急性偏瘫的“白索综合征”
World Neurosurg. 2018 May;113:33-36. doi: 10.1016/j.wneu.2018.02.026. Epub 2018 Feb 13.
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Specific pattern of gadolinium enhancement in spondylotic myelopathy.颈椎病性脊髓病的特定钆增强模式。
Ann Neurol. 2014 Jul;76(1):54-65. doi: 10.1002/ana.24184. Epub 2014 Jun 14.
7
"White cord syndrome" of acute tetraplegia after anterior cervical decompression and fusion for chronic spinal cord compression: a case report.慢性脊髓压迫症前路颈椎减压融合术后急性四肢瘫的“白脊髓综合征”:一例报告
Case Rep Orthop. 2013;2013:697918. doi: 10.1155/2013/697918. Epub 2013 Mar 4.
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Spinal cord swelling with abnormal gadolinium-enhancement mimicking intramedullary tumors in cervical spondylosis patients: Three case reports and review of the literature.脊髓型颈椎病患者脊髓肿胀伴异常钆增强,类似髓内肿瘤:三例报告并文献复习
Asian J Neurosurg. 2010 Jul;5(2):1-9.
9
Clinical significance of intramedullary Gd-DTPA enhancement in cervical myelopathy.颈脊髓病骨髓腔内 Gd-DTPA 增强的临床意义。
Spinal Cord. 2010 May;48(5):415-22. doi: 10.1038/sc.2009.152. Epub 2009 Nov 10.
10
Patterns of contrast enhancement in the brain and meninges.脑和脑膜的对比增强模式。
Radiographics. 2007 Mar-Apr;27(2):525-51. doi: 10.1148/rg.272065155.