• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用或不使用前路钢板的独立颈椎椎间融合器治疗多节段颈椎间盘疾病:一项前瞻性随机对照研究。

Treatment of multilevel cervical disc disease with standalone cervical cages with or without anterior plating: A prospective randomized comparative study.

作者信息

Abousayed Mahmoud, Elmiligui Yasser, Koptan Wael, Elhamaky Mostafa, Barakat Ahmed Samir, Sultan Ahmed Maher

机构信息

Department of Trauma and Orthopaedics, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

J Craniovertebr Junction Spine. 2025 Jan-Mar;16(1):89-95. doi: 10.4103/jcvjs.jcvjs_148_24. Epub 2025 Apr 1.

DOI:10.4103/jcvjs.jcvjs_148_24
PMID:40292164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12029388/
Abstract

PURPOSE

The purpose of the study was to compare the results of anterior cervical discectomy and fusion (ACDF) using standalone cages versus cages with anterior plating for multilevel cervical disc disease with a 2-year follow-up.

BACKGROUND

ACDF is a commonly performed procedure in cases of neural compression caused by osteophytes or disc material. Some spine surgeons have reported unsatisfactory outcomes and fusion rates secondary to a high rate of cage subsidence and pseudoarthrosis. Internal fixation using anterior cervical plate has been developed as an adjunct to ACDF to enhance the stability provided by the intervertebral cages.

PATIENTS AND METHODS

A total number of 60 consecutive patients diagnosed with multilevel cervical disc disease (two or more) underwent ACDF with or without additional anterior plating, between August 2021 and March 2022. Only 50 patients completed the follow-up which was ranged from 20 to 26 months.

RESULTS

There were no significant differences between the two groups regarding age and sex. Comparing the pre and postoperative Visual Analog Scale (VAS) for both neck pain and brachialgia and neck disability index (NDI) in both groups was statistically significant. There was no significant statistical difference between the two groups regarding the postoperative clinical outcomes. There was a significant statistical difference in the fused segment lordotic angle (FSA) being greater in the plating group.

CONCLUSION

The use of stand-alone cages in two-level ACDF or more in our study had a shorter operative time and hospital stay when compared to ACDF with anterior plating with greater FSA in the plate group but with no difference in clinical outcome after 2-year follow-up.

摘要

目的

本研究的目的是比较使用独立椎间融合器与带前路钢板的椎间融合器进行颈椎前路椎间盘切除融合术(ACDF)治疗多节段颈椎间盘疾病并进行2年随访的结果。

背景

ACDF是治疗由骨赘或椎间盘组织引起神经压迫病例的常用手术。一些脊柱外科医生报告称,由于椎间融合器下沉率和假关节形成率较高,导致治疗效果和融合率不尽人意。使用颈椎前路钢板进行内固定已被开发作为ACDF的辅助手段,以增强椎间融合器提供的稳定性。

患者和方法

2021年8月至2022年3月期间,共有60例连续诊断为多节段颈椎间盘疾病(两节或以上)的患者接受了有或没有额外前路钢板固定的ACDF手术。只有50例患者完成了随访,随访时间为20至26个月。

结果

两组在年龄和性别方面无显著差异。比较两组术前和术后颈部疼痛和臂丛神经痛的视觉模拟量表(VAS)以及颈部功能障碍指数(NDI),差异具有统计学意义。两组术后临床结果无显著统计学差异。钢板固定组融合节段前凸角(FSA)更大,差异具有统计学意义。

结论

在我们的研究中,与使用前路钢板的ACDF相比,在两节或更多节段的ACDF中使用独立椎间融合器手术时间更短,住院时间更短,钢板固定组的FSA更大,但2年随访后临床结果无差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/83c602835e05/JCVJS-16-89-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/3fb4176648ad/JCVJS-16-89-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/814be6c43176/JCVJS-16-89-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/83c602835e05/JCVJS-16-89-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/3fb4176648ad/JCVJS-16-89-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/814be6c43176/JCVJS-16-89-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e43/12029388/83c602835e05/JCVJS-16-89-g003.jpg

相似文献

1
Treatment of multilevel cervical disc disease with standalone cervical cages with or without anterior plating: A prospective randomized comparative study.使用或不使用前路钢板的独立颈椎椎间融合器治疗多节段颈椎间盘疾病:一项前瞻性随机对照研究。
J Craniovertebr Junction Spine. 2025 Jan-Mar;16(1):89-95. doi: 10.4103/jcvjs.jcvjs_148_24. Epub 2025 Apr 1.
2
A comparison of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone polyetheretherketone (PEEK) cage with ACDF using cage and plate in the treatment of three-level cervical degenerative spondylopathy: a retrospective study with 2-year follow-up.使用自锁独立聚醚醚酮(PEEK)椎间融合器的颈椎前路椎间盘切除融合术(ACDF)与使用椎间融合器和钢板的ACDF治疗三级颈椎退行性脊椎病的比较:一项为期2年随访的回顾性研究
Eur Spine J. 2016 Jul;25(7):2255-62. doi: 10.1007/s00586-016-4391-x. Epub 2016 Feb 23.
3
A Prospective Study with Cage-Only or Cage-with-Plate Fixation in Anterior Cervical Discectomy and Interbody Fusion of One and Two Levels.单节段和双节段颈椎前路椎间盘切除及椎间融合术中单纯椎间融合器或椎间融合器联合钢板固定的前瞻性研究
J Korean Neurosurg Soc. 2017 Nov;60(6):691-700. doi: 10.3340/jkns.2017.0211. Epub 2017 Oct 25.
4
Can Self-Locking Cages Offer the Same Clinical Outcomes as Anterior Cage-with-Plate Fixation for 3-Level Anterior Cervical Discectomy and Fusion (ACDF) in Mid-Term Follow-Up?自锁 Cage 是否能在中期随访中获得与前路 Cage-钢板固定相同的临床效果?用于治疗三节段前路颈椎间盘切除融合术(ACDF)
Med Sci Monit. 2019 Jan 19;25:547-557. doi: 10.12659/MSM.911234.
5
Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft.前路颈椎间盘切除及可植入钛笼融合术:初步印象、患者预后及与同种异体骨融合术的比较
Spine J. 2004 Mar-Apr;4(2):184-91; discussion 191. doi: 10.1016/j.spinee.2003.05.001.
6
Stand-Alone Cervical Cages in 2-Level Anterior Interbody Fusion in Cervical Spondylotic Myelopathy: Results from a Minimum 2-Year Follow-up.独立颈椎椎间融合器用于脊髓型颈椎病双节段前路椎间融合术:至少2年随访结果
Asian Spine J. 2019 Apr;13(2):225-232. doi: 10.31616/asj.2018.0193. Epub 2018 Nov 27.
7
Influence of plate fixation on cervical height and alignment after one- or two-level anterior cervical discectomy and fusion.单节段或双节段颈椎前路椎间盘切除融合术后钢板固定对颈椎高度及对线的影响。
Br J Neurosurg. 2018 Apr;32(2):188-195. doi: 10.1080/02688697.2017.1394980. Epub 2017 Oct 26.
8
Does two-level hybrid surgery promote early fusion compared with two-level anterior cervical discectomy and fusion?与两级颈椎前路椎间盘切除融合术相比,两级混合手术是否能促进早期融合?
Spine J. 2025 Jun;25(6):1167-1177. doi: 10.1016/j.spinee.2024.12.022. Epub 2024 Dec 18.
9
Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation.多级颈椎前路椎间盘切除融合术联合刚性钢板固定中同种异体移植与自体移植的比较。
Spine J. 2003 Nov-Dec;3(6):451-9. doi: 10.1016/s1529-9430(03)00173-6.
10
A comparison of a self-locking stand-alone cage and anterior cervical plate for ACDF: Minimum 3-year assessment of radiographic and clinical outcomes.自锁独立椎间融合器与颈椎前路钢板用于颈椎前路椎间盘切除融合术的比较:影像学及临床结果的至少3年评估
Clin Neurol Neurosurg. 2018 Jul;170:73-78. doi: 10.1016/j.clineuro.2018.04.033. Epub 2018 Apr 30.

本文引用的文献

1
Multilevel anterior cervical fusion with standalone cage or cage-and-plate after cervical discectomy: Benefits and drawbacks.颈椎间盘切除术后采用单纯 cage 或 cage-and-plate 进行多层前路颈椎融合:优缺点。
Asian J Surg. 2023 Sep;46(9):3760-3765. doi: 10.1016/j.asjsur.2023.02.032. Epub 2023 Feb 22.
2
Stand-Alone Cage Versus Anterior Plating for 1-Level and 2-Level Anterior Cervical Discectomy and Fusion: A Randomized Controlled Trial.单节段和双节段颈椎前路椎间盘切除融合术:独立椎间融合器与前路钢板固定的随机对照试验
Clin Spine Surg. 2022 May 1;35(4):155-165. doi: 10.1097/BSD.0000000000001332. Epub 2022 Apr 11.
3
Comparison of Clinical and Radiographic Outcomes After Standalone Versus Cage and Plate Constructs for Anterior Cervical Discectomy and Fusion.
单纯前路颈椎间盘切除融合术与椎间融合器加钢板植入融合术的临床及影像学结果比较
Int J Spine Surg. 2021 Jun;15(3):403-412. doi: 10.14444/8060. Epub 2021 May 7.
4
Comparison of Anterior Cervical Discectomy and Fusion With a Stand-Alone Interbody Cage Versus a Conventional Cage-Plate Technique: A Systematic Review and Meta-Analysis.前路颈椎间盘切除融合术:独立椎间融合器与传统椎间融合器钢板技术的比较:系统评价与Meta分析
Global Spine J. 2019 Jun;9(4):446-455. doi: 10.1177/2192568218774576. Epub 2018 May 17.
5
Comparison of the outcomes of cage-stand-alone with cage-with-plate fixation in one level and two levels for treating cervical disk diseases.单节段和双节段颈椎间盘疾病治疗中单纯椎间融合器与椎间融合器联合钢板固定的疗效比较。
J Craniovertebr Junction Spine. 2018 Jul-Sep;9(3):170-174. doi: 10.4103/jcvjs.JCVJS_74_18.
6
A Prospective Study with Cage-Only or Cage-with-Plate Fixation in Anterior Cervical Discectomy and Interbody Fusion of One and Two Levels.单节段和双节段颈椎前路椎间盘切除及椎间融合术中单纯椎间融合器或椎间融合器联合钢板固定的前瞻性研究
J Korean Neurosurg Soc. 2017 Nov;60(6):691-700. doi: 10.3340/jkns.2017.0211. Epub 2017 Oct 25.
7
Cage with anterior plating is advantageous over the stand-alone cage for segmental lordosis in the treatment of two-level cervical degenerative spondylopathy: A retrospective study.前路钢板融合椎间融合器治疗双节段颈椎退变性脊柱病在恢复节段前凸方面优于单纯椎间融合器:一项回顾性研究。
Clin Neurol Neurosurg. 2017 Dec;163:27-32. doi: 10.1016/j.clineuro.2017.10.014. Epub 2017 Oct 16.
8
A comparison of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone polyetheretherketone (PEEK) cage with ACDF using cage and plate in the treatment of three-level cervical degenerative spondylopathy: a retrospective study with 2-year follow-up.使用自锁独立聚醚醚酮(PEEK)椎间融合器的颈椎前路椎间盘切除融合术(ACDF)与使用椎间融合器和钢板的ACDF治疗三级颈椎退行性脊椎病的比较:一项为期2年随访的回顾性研究
Eur Spine J. 2016 Jul;25(7):2255-62. doi: 10.1007/s00586-016-4391-x. Epub 2016 Feb 23.
9
Cervical spondylotic myelopathy: pathophysiology, clinical presentation, and treatment.脊髓型颈椎病:病理生理学、临床表现和治疗。
HSS J. 2011 Jul;7(2):170-8. doi: 10.1007/s11420-011-9208-1. Epub 2011 Jun 22.
10
Stand-alone cervical cages versus anterior cervical plate in 2-level cervical anterior interbody fusion patients: clinical outcomes and radiologic changes.单节段颈椎椎间融合器与颈椎前路钢板用于双节段颈椎前路椎间融合术患者的比较:临床疗效及影像学变化
J Spinal Disord Tech. 2013 Dec;26(8):415-20. doi: 10.1097/BSD.0b013e31824c7d22.