溶血血小板激活因子从豚鼠肺中的释放。
The release of lyso-PAF from guinea-pig lungs.
作者信息
Parente L, Fitzgerald M, De Nucci G, Moncada S
出版信息
Eur J Pharmacol. 1985 Jun 7;112(2):281-4. doi: 10.1016/0014-2999(85)90511-4.
PMID:4029263
Abstract
Lyso-PAF was detected after ionophore challenge in the effluent of lungs of guinea-pigs exposed to oxygen and perfused through the pulmonary circulation as well as of control lungs perfused through the airways. Lyso-PAF is probably the inactive metabolite of PAF-acether which could not, itself, be detected in the lung effluents.
摘要
在经离子载体激发后，在暴露于氧气并经肺循环灌注的豚鼠肺脏流出物中，以及经气道灌注的对照肺脏流出物中，均可检测到溶血血小板活化因子（Lyso-PAF）。溶血血小板活化因子可能是血小板活化因子乙酰醚（PAF-acether）的无活性代谢产物，而血小板活化因子乙酰醚本身在肺脏流出物中无法检测到。
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