Reese B E, Cowey A
Exp Brain Res. 1985;59(2):372-81. doi: 10.1007/BF00230917.
The superior colliculus was bilaterally or unilaterally ablated at different early postnatal ages in rats. When adult, each rat received a unilateral eye injection of Horseradish peroxidase to reveal the crossed and uncrossed retinal terminal fields within the dorsal lateral geniculate nucleus. Collicular ablation in the first seven days after birth, but not thereafter, produced a small hole or vacancy within the contralateral retinal terminal field which was occupied by an aberrant ipsilateral retinal terminal field. These rearrangements in the retino-geniculate projections occurred in the caudal quarter of the nucleus dorso-laterally just beneath the optic tract, solely ipsilateral to the ablated colliculus. Possible causes of the formation of these rearrangements are discussed, and similarities with other aberrant retinal projections following early damage to the visual system are considered.
在出生后不同的早期阶段，对大鼠的上丘进行双侧或单侧切除。成年后，每只大鼠接受单侧眼注射辣根过氧化物酶，以显示背外侧膝状核内交叉和未交叉的视网膜终末场。出生后前七天进行上丘切除，但之后切除则不会，这会在对侧视网膜终末场内产生一个小孔或空缺，该空缺被异常的同侧视网膜终末场所占据。这些视网膜-膝状体投射的重排发生在背外侧核尾侧四分之一处，恰好在视束下方，仅在切除上丘的同侧。文中讨论了这些重排形成的可能原因，并考虑了与视觉系统早期损伤后其他异常视网膜投射的相似性。
