Lei Wei, Huang Yi, Peng Yanjie, Chen Guangxiang, Gong Ke, Liu Kezhi, Wu Dantong, Qin Cheng, Cheng Xiaotong, Tian Mingyuan, Zhang Luoya, Zhou Yanyin, Yu Rongjun, Chen Jing
1Department of Psychiatry, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
2Laboratory of Neurological Diseases and Brain Function, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
J Behav Addict. 2025 Apr 28;14(2):831-845. doi: 10.1556/2006.2025.00037. Print 2025 Jul 2.
BACKGROUND AND AIMS: The shift from goal-directed to habitual control is a well-documented phenomenon in addiction research and is considered a critical factor in the development and maintenance of addictive behaviors. Whether Internet Gaming Disorder (IGD) is also associated with such a shift is not yet clear. The current study investigated the imbalance between goal-directed and habitual control in individuals with IGD. METHODS: Goal-directed and habitual control, as informed by model-based (MB) and model-free (MF) learning, were assessed with a two-step sequential decision-making task during functional magnetic resonance imaging (fMRI) in 33 young adults with IGD and 32 healthy controls (HCs). Self-report data regarding addictive symptoms, game craving, and impulsivity were also collected. RESULTS: Individuals with IGD relied more heavily on habitual control to guide subsequent choices compared to HCs. According to a hybrid reinforcement learning model, individuals with IGD also exhibited a reduced MB weight related to HCs, which was correlated with more severe addictive symptoms. fMRI results revealed that individuals with IGD showed increased MF reward prediction error (RPEMF) signals in the right triangular part of the inferior frontal gyrus (IFG). No significant group differences were found in the contrast of RPEMB maps. DISCUSSION AND CONCLUSIONS: Our study provides both behavioral and neural evidence highlighting an imbalance between goal-directed and habitual control, favoring habitual control in individuals with IGD. This imbalance is associated with the severity of addictive symptoms, suggesting an indication of habit inclination in IGD could potentially contribute to the development or maintenance of the addiction.
背景与目的:从目标导向控制向习惯性控制的转变是成瘾研究中一个有充分文献记载的现象,被认为是成瘾行为发展和维持的关键因素。网络成瘾障碍(IGD)是否也与这种转变相关尚不清楚。本研究调查了IGD个体中目标导向控制与习惯性控制之间的失衡情况。 方法:在33名患有IGD的年轻成年人和32名健康对照者(HCs)进行功能磁共振成像(fMRI)期间,通过两步顺序决策任务评估基于模型(MB)和无模型(MF)学习所反映的目标导向控制和习惯性控制。还收集了关于成瘾症状、游戏渴望和冲动性的自我报告数据。 结果:与HCs相比,IGD个体在指导后续选择时更依赖习惯性控制。根据混合强化学习模型,IGD个体与HCs相比还表现出与MB权重降低,这与更严重的成瘾症状相关。fMRI结果显示,IGD个体在右下额叶回(IFG)的右侧三角部分表现出MF奖励预测误差(RPEMF)信号增加。在RPEMB图谱的对比中未发现显著的组间差异。 讨论与结论:我们的研究提供了行为和神经方面的证据,突出了目标导向控制与习惯性控制之间的失衡,在IGD个体中更倾向于习惯性控制。这种失衡与成瘾症状的严重程度相关,表明IGD中习惯倾向的迹象可能有助于成瘾的发展或维持。
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