Siegel M, Krantz B, Lebenthal E
Gastroenterology. 1985 Oct;89(4):785-90. doi: 10.1016/0016-5085(85)90573-6.
The gastric emptying of six infant feedings (20 kcal/oz; whey to casein ratio, 60:40) with varying fat and carbohydrate composition was studied. Feedings contained either predominantly long-chain triglycerides (94%) or predominantly medium-chain triglycerides (94%) as the fat and lactose, glucose, or glucose polymers (Polycose) as the carbohydrate. Eleven premature infants were fed 22 ml/kg body wt of all six feedings over a 3-4-day period, and the volume of gastric contents was measured every 20 min using polyethylene glycol 4000 as the marker. Analysis of variance demonstrated that the use of medium-chain triglycerides resulted in faster gastric emptying than long-chain triglycerides (p less than 0.001). Analysis of variance and Tukey's test showed that use of glucose polymers instead of glucose resulted in less volume of gastric contents at 40 min (p less than 0.05). Use of glucose polymers instead of lactose resulted in less volume of gastric contents at 60 and 80 min (p less than 0.05). Gastric emptying can be altered by changes in nutrient composition. The difference between medium-chain and long-chain triglycerides was more pronounced than the differences between the carbohydrates studied. Feedings with medium-chain triglycerides may be more suitable than long-chain triglycerides in patients with delayed gastric emptying.
研究了六种婴儿配方奶（20千卡/盎司；乳清与酪蛋白比例为60:40）在脂肪和碳水化合物组成不同时的胃排空情况。配方奶中的脂肪要么主要是长链甘油三酯（94%），要么主要是中链甘油三酯（94%），碳水化合物则为乳糖、葡萄糖或葡萄糖聚合物（聚葡萄糖）。11名早产儿在3 - 4天内按每千克体重22毫升的量喂食了所有六种配方奶，并使用聚乙二醇4000作为标记物，每隔20分钟测量一次胃内容物的体积。方差分析表明，使用中链甘油三酯时胃排空比长链甘油三酯更快（p<0.001）。方差分析和Tukey检验显示，使用葡萄糖聚合物而非葡萄糖时，40分钟时胃内容物体积更小（p<0.05）。使用葡萄糖聚合物而非乳糖时，60分钟和80分钟时胃内容物体积更小（p<0.05）。营养成分的改变可影响胃排空。中链甘油三酯与长链甘油三酯之间的差异比所研究的碳水化合物之间的差异更为显著。对于胃排空延迟的患者，含中链甘油三酯的配方奶可能比含长链甘油三酯的配方奶更合适。
