Frischbier H J, Wenn K
Geburtshilfe Frauenheilkd. 1985 Jul;45(7):494-6. doi: 10.1055/s-2008-1036359.
Between 1965 and 1979 vulvectomy was performed in 41 patients because of histologically demonstrated local recurrence of a vulval carcinoma after electron beam therapy. Of the patients thus treated, 36.6% survived more than 3 years and 19.5% more than 5 years. An analysis of this group of patients shows that only recurrences less than 3 cm in size have a good prognosis with secondary vulvectomy. However, even with a more severe local condition, a secondary vulvectomy is justified as a palliative. Previous electron beam therapy does not represent an absolute contraindication to surgery, even though there may only be secondary healing in almost all cases.
1965年至1979年间，41例患者因组织学证实外阴癌在电子束治疗后局部复发而接受了外阴切除术。在接受如此治疗的患者中，36.6%存活超过3年，19.5%存活超过5年。对这组患者的分析表明，只有直径小于3 cm的复发病例经二次外阴切除术后预后良好。然而，即使局部病情更严重，二次外阴切除术作为一种姑息性手术也是合理的。既往的电子束治疗并非手术的绝对禁忌证，尽管几乎所有病例术后可能仅有二期愈合。
