Nover Jonathan, Bai Mathew, Tismina Prem, Raut Ganesh, Patel Dhavalkumar, Nadkarni Girish N, Abella Benjamin S, Klang Eyal, Freeman Robert
Department of Emergency Medicine, Mount Sinai Health System, New York, NY 10029, United States.
The Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Medical Center, NY, USA.
medRxiv. 2025 Apr 8:2025.04.07.25325126. doi: 10.1101/2025.04.07.25325126.
Emergency department (ED) crowding strains patient care and drives up costs. Early decisions on the need for patient hospital admissions can allow for better planning and potentially improve throughput and alleviate crowding. We sought to prospectively compare nurse predictions with a machine learning (ML) model for hospital admissions and to evaluate whether adding the nurse prediction to ML outputs enhances predictive performance.
In this prospective, observational study at six hospitals in a large mixed quarternary/community ED system (annual ED census ~500,000), triage nurses recorded a binary admission prediction for adult patients. These predictions were compared with an ensemble ML model (XGBoost + Bio-Clinical BERT) trained on structured data (demographics, vital signs, medical history) and triage text. Nurse predictions were similarly analyzed and then integrated with the ML output to assess for improvement in predictive accuracy.
The ensemble ML model (XGBoost + Bio-Clinical BERT) was trained on 1.8 million historical ED visits (January 2019-December 2023). It was then tested on 46,912 prospective ED visits with recorded nurse predictions (September to October 2024). In the prospective arm, nurse predictions yielded an accuracy of 81.6% (95% CI, 81.3-81.9), sensitivity of 64.8% (63.7-65.8), and specificity of 85.7% (85.3-86.0). At a 0.30 probability threshold, the ML model attained an accuracy of 85.4% (85.0-85.7) and sensitivity of 70.8% (69.8-71.7). Combining nurse predictions with the ML output did not improve accuracy beyond the model alone.
Machine learning-based predictions outperformed triage nurse estimates for hospital admissions. These findings suggest that an admission prediction system anchored by ML can perform reliably using data available at triage.
急诊科拥挤状况给患者护理带来压力并导致成本上升。对患者住院需求尽早做出决策有助于更好地规划,并有可能提高就诊量和缓解拥挤状况。我们旨在前瞻性地比较护士的预测与用于住院预测的机器学习(ML)模型,并评估将护士的预测添加到ML输出中是否能提高预测性能。
在一个大型混合四级/社区急诊科系统(急诊科年接诊量约50万)的六家医院进行的这项前瞻性观察研究中,分诊护士记录了成年患者的二元住院预测。将这些预测与基于结构化数据(人口统计学、生命体征、病史)和分诊文本训练的集成ML模型(XGBoost + 生物临床BERT)进行比较。对护士的预测进行类似分析,然后与ML输出相结合,以评估预测准确性的提高情况。
集成ML模型(XGBoost + 生物临床BERT)基于180万次历史急诊科就诊记录(2019年1月至2023年12月)进行训练。然后在46,912次有记录护士预测的前瞻性急诊科就诊中进行测试(2024年9月至10月)。在前瞻性队列中,护士的预测准确率为81.6%(95%CI,81.3 - 81.9),灵敏度为64.8%(63.7 - 65.8),特异度为85.7%(85.3 - 86.0)。在概率阈值为0.30时,ML模型的准确率为85.4%(85.0 - 85.7),灵敏度为70.8%(69.8 - 71.7)。将护士的预测与ML输出相结合并没有比单独使用模型提高准确性。
基于机器学习的住院预测优于分诊护士的估计。这些发现表明,以ML为基础的住院预测系统可以利用分诊时可用的数据可靠地运行。