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美国国家辐射防护与测量委员会称六项研究支持线性无阈模型,但这些研究表明在至少100毫戈瑞时无效应。

NCRP Claims Six Studies Support LNT But They Show No-Effect to At Least 100 mGy.

作者信息

Chaplin K

机构信息

Canadian Nuclear Laboratories - Retired, Chalk River, ON, Canada.

出版信息

Dose Response. 2025 Apr 15;23(2):15593258251329682. doi: 10.1177/15593258251329682. eCollection 2025 Apr-Jun.

Abstract

NCRP Commentary-27 reaffirmed Linear No Threshold (LNT) as the basis for radiation protection and listed six studies with "strong support" for LNT. This paper looks critically at these six studies and shows that they do not support LNT in the dose range of 0-100 mGy. These studies typically admit to no increase in cancer risk at significant dose levels. More importantly this paper shows that these studies assume LNT from the outset, underestimate uncertainty, ignore confounding factors, have biased control groups, and underestimate dose.

摘要

NCRP评论-27重申线性无阈(LNT)作为辐射防护的基础,并列出六项对LNT有“有力支持”的研究。本文批判性地审视了这六项研究,并表明它们在0至100毫戈瑞的剂量范围内并不支持LNT。这些研究通常承认在显著剂量水平下癌症风险没有增加。更重要的是,本文表明这些研究从一开始就假定LNT,低估了不确定性,忽略了混杂因素,对照组存在偏差,并且低估了剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2e9/12033839/90a6a7c3cf53/10.1177_15593258251329682-fig1.jpg

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