Colucci Ligia, Rengifo Jaime
From the Clínica Colucci, Private Practice, Rua Ouro Preto 1596 Sl 902, Santo Agostinho, Belo Horizonte, Minas Gerais CEP 30170-048, Brazil.
Universidad Pontificia Bolivariana, Medellín, Colombia.
Plast Reconstr Surg Glob Open. 2025 Apr 28;13(4):e6668. doi: 10.1097/GOX.0000000000006668. eCollection 2025 Apr.
Facial aging entails complex alterations across various tissues, prompting individuals to seek aesthetic interventions. The anatomical complexities of the facial upper third and its proximity to vital vascular structures provide inherent risks. We aim to identify and elucidate the safety considerations and avenues for improvement regarding established injection sites and techniques for hyaluronic acid fillers in this area, encompassing the forehead and temporal region.
We conducted a comprehensive literature search across PubMed, Embase, LILACS, and OpenGrey. Eligible studies were analyzed for injection sites, techniques, safety considerations, and anatomical landmarks. Qualitative synthesis and critical appraisal were used to identify trends, variations, and areas of consensus or controversy. Additionally, medical illustrations were created to deliver a practical overview. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist and the Joanna Briggs Institute's scoping review recommendations.
We included 7 studies in the review. Common injection sites included frontal and temporal regions, with variations in techniques noted across studies. Trends in filler placement and techniques were observed alongside several areas of controversy requiring further investigation.
We underscore the absence of a standardized approach to hyaluronic acid filler injection sites and techniques for the facial upper third. Integrating anatomical knowledge with empirical evidence will be paramount in developing standardized techniques that prioritize patient safety and enhance treatment efficacy.
面部衰老涉及多种组织的复杂变化，促使人们寻求美容干预。面部上三分之一的解剖结构复杂，且靠近重要血管结构，存在固有风险。我们旨在确定并阐明该区域（包括额头和颞部）透明质酸填充剂既定注射部位和技术的安全考量及改进途径。
我们在PubMed、Embase、LILACS和OpenGrey上进行了全面的文献检索。对符合条件的研究进行分析，以确定注射部位、技术、安全考量和解剖标志。采用定性综合和批判性评价来识别趋势、差异以及共识或争议领域。此外，还制作了医学插图以提供实用概述。我们遵循系统评价和Meta分析扩展版的范围审查清单的首选报告项目以及乔安娜·布里格斯研究所的范围审查建议。
我们纳入了7项研究进行综述。常见的注射部位包括额部和颞部，各研究中技术存在差异。观察到填充剂放置和技术的趋势，同时也有几个争议领域需要进一步研究。
我们强调面部上三分之一的透明质酸填充剂注射部位和技术缺乏标准化方法。将解剖学知识与经验证据相结合对于开发优先考虑患者安全并提高治疗效果的标准化技术至关重要。
