Li Tianjiao, Alonso Flavio H, Rhoades Amy, Kelman Alina, Affolter Verena, Sykes Jane E
Veterinary Medical Teaching Hospital, University of California-Davis, Davis, California, USA.
Department of Comparative Medicine, School of Medicine, Stanford University, Stanford, California, USA.
J Vet Intern Med. 2025 May-Jun;39(3):e70083. doi: 10.1111/jvim.70083.
Mycobacterium fortuitum mycobacteremia and arthritis were diagnosed in a Briard dog from northern California. The dog was evaluated for lameness and had a history of immunosuppressive treatment and splenectomy for refractory immune thrombocytopenia. Cytological examination of synovial fluid from the right tarsus indicated marked suppurative inflammation with intralesional acid-fast bacteria. Mycobacterium fortuitum was cultured from joint fluid and blood; identification was based on PCR sequencing. Diagnosis was complicated by initial misidentification of the organism as an Actinomyces species. The dog was successfully treated with clarithromycin and enrofloxacin. The dog was later treated for a Grade III mast cell tumor of the thoracic limb with radiation therapy and chemotherapy and then died 2 years after the diagnosis of mycobacteremia because of extradural hemangiosarcoma of the spine.
在一只来自加利福尼亚北部的布里牧犬身上诊断出偶然分枝杆菌菌血症和关节炎。这只狗因跛行接受评估，有因难治性免疫性血小板减少症接受免疫抑制治疗和脾切除术的病史。对右跗关节滑液的细胞学检查显示有明显的化脓性炎症，病灶内有抗酸菌。从关节液和血液中培养出偶然分枝杆菌；通过聚合酶链反应测序进行鉴定。诊断因最初将该菌误鉴定为放线菌属而变得复杂。这只狗用克拉霉素和恩诺沙星成功治疗。这只狗后来因前肢三级肥大细胞瘤接受放疗和化疗，在诊断菌血症2年后因脊柱硬膜外血管肉瘤死亡。
