一种用于调查乳腺癌幸存者日常认知功能的新型生态瞬时评估应用程序：一项可行性研究。

A novel ecological momentary assessment app for the investigation of daily cognitive functioning in breast cancer survivors: a feasibility study.

作者信息

Cobden Annalee L, Burnett Jake, Saward Jacqueline B, Burmester Alex, Singh Mervyn, Domínguez D Juan F, Gates Priscilla, Lippey Jocelyn, Caeyenberghs Karen

机构信息

Cognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Australia.

Neuroplasticity and Multimodal Imaging (NMI) Lab, Cognitive Neuroscience Unit, School of Psychology, Deakin University, Melbourne Burwood Campus, 221 Burwood Highway, Burwood, VIC, 3125, Australia.

出版信息

Support Care Cancer. 2025 Apr 29;33(5):434. doi: 10.1007/s00520-025-09470-1.

DOI:10.1007/s00520-025-09470-1

PMID:40299155

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12041178/

Abstract

PURPOSE

Breast cancer survivors often experience cancer-related cognitive impairment (CRCI), such as problems with memory and attention. However, typical neuropsychological test batteries are unable to capture the day-to-day variability of cognition and may be underestimating CRCI. The present study aims to assess the feasibility, usability, and validity of a novel ecological momentary assessment (EMA) app of cognition.

METHODS

Nineteen breast cancer survivors 6-36-month post-chemotherapy and 28 healthy controls completed the NIH Toolbox Cognition Battery. Subsequently, participants completed the EMA app (once a day, for 30 days) comprising four cognitive tasks assessing processing speed, working memory, inhibition, and attention. At the conclusion of the app, participants completed a usability questionnaire on which content analysis was performed. Feasibility was assessed against eight criteria, including accessibility, app compliance, and technical smoothness. Convergent construct validity was assessed using Spearman's correlation analyses between the NIH toolbox and the EMA app.

RESULTS

Five of eight feasibility criteria were met, including accessibility, app motivation, participation rate, drop-out, and data collection. Additionally, our content analyses revealed four themes important to usability: self-development, altruism, engagement, and functionality. Majority of the EMA tasks were moderately positively correlated with the corresponding constructs of the NIH toolbox tasks (R's range 0.55-0.64), indicating better performance on the EMA app coincided with better performance on the NIH toolbox.

CONCLUSIONS

Our findings show the app was accessible, participants were motivated to complete sessions, and our tasks showed good construct validity.

IMPLICATIONS FOR CANCER SURVIVORS

Our novel EMA app can be used as a comprehensive cognitive measure in cancer survivors.

摘要

目的

乳腺癌幸存者常经历与癌症相关的认知障碍（CRCI），如记忆和注意力问题。然而，典型的神经心理学测试组合无法捕捉认知的日常变异性，可能会低估CRCI。本研究旨在评估一种新型认知生态瞬时评估（EMA）应用程序的可行性、可用性和有效性。

方法

19名化疗后6至36个月的乳腺癌幸存者和28名健康对照者完成了美国国立卫生研究院（NIH）工具箱认知测试组合。随后，参与者完成了EMA应用程序（每天一次，共30天），该应用程序包含四项认知任务，评估处理速度、工作记忆、抑制和注意力。在应用程序结束时，参与者完成了一份可用性问卷，并进行了内容分析。根据八个标准评估可行性，包括可及性、应用程序依从性和技术流畅性。使用NIH工具箱与EMA应用程序之间的斯皮尔曼相关性分析评估聚合建构效度。

结果

八项可行性标准中的五项得到满足，包括可及性、应用程序动机、参与率、退出率和数据收集。此外，我们的内容分析揭示了对可用性重要的四个主题：自我发展、利他主义、参与度和功能性。大多数EMA任务与NIH工具箱任务的相应建构呈中度正相关（R值范围为0.55 - 0.64），表明EMA应用程序上的表现更好与NIH工具箱上的表现更好相吻合。