Wang Xiaotian, Li Meijia, Tian Yuan, Chen Xinyao, Li Jiapeng, Luo Sai, Hao Lijun
The Center of Plastic and Aesthetic Surgery of the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, People's Republic of China.
Aesthetic Plast Surg. 2025 Apr 29. doi: 10.1007/s00266-025-04792-1.
Nostril overexposure is a common aesthetic concern among Asian populations, which significantly affects facial harmony. Traditional surgical interventions carry risks such as substantial trauma and visible scarring. This study aims to evaluate the clinical efficacy of Botulinum Toxin Type A (BoNT-A) injections in treating nostril overexposure using three-dimensional (3D) scanning technology.
This study recruited 52 patients seeking improvement for nostril overexposure. BoNT-A was injected into the nasal dilator muscles. Changes in nostril cross-sectional area and alar mobility were quantified using 3D scanning technology before treatment and at 4, 12, and 24 weeks post-treatment. Subjective improvements were evaluated by patients and one independent plastic surgery experts using the Global Aesthetic Improvement Scale (GAIS).
A total of 32 patients completed the entire 24-week follow-up period. Post-treatment 3D analysis showed a significant reduction in both nostril cross-sectional area and alar mobility. At 4 weeks post-injection, the nostril area decreased from 89.42 ± 13.21 to 72.50 ± 13.93 mm (p < 0.05), and alar mobility decreased from 10.50 ± 3.92 to 4.64 ± 3.09% (p < 0.05). GAIS scores indicated that both patients and expert rated the improvement as significant at 4 weeks. Measurements at 24 weeks approached baseline levels.
BoNT-A injections effectively and safely improve nostril overexposure with high patient satisfaction.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
鼻孔过度暴露是亚洲人群常见的美学问题，严重影响面部和谐。传统手术干预存在诸如严重创伤和明显瘢痕等风险。本研究旨在使用三维（3D）扫描技术评估A型肉毒杆菌毒素（BoNT-A）注射治疗鼻孔过度暴露的临床疗效。
本研究招募了52例寻求改善鼻孔过度暴露的患者。将BoNT-A注射到鼻扩张肌中。在治疗前以及治疗后4周、12周和24周，使用3D扫描技术对鼻孔横截面积和鼻翼活动度的变化进行量化。患者和一名独立的整形外科专家使用全球美学改善量表（GAIS）评估主观改善情况。
共有32例患者完成了整个24周的随访期。治疗后的3D分析显示鼻孔横截面积和鼻翼活动度均显著降低。注射后4周，鼻孔面积从89.42±13.21减小至72.50±13.93平方毫米（p<0.05），鼻翼活动度从10.50±3.92%降至4.64±3.09%（p<0.05）。GAIS评分表明，患者和专家均在4周时将改善情况评为显著。24周时的测量结果接近基线水平。
BoNT-A注射有效且安全地改善了鼻孔过度暴露，患者满意度高。
证据等级IV：本刊要求作者为每篇文章指定证据等级。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南www.springer.com/00266 。
