Sankaranarayanan A, Goel A, Pant V L
Int J Clin Pharmacol Ther Toxicol. 1985 Jul;23(7):365-6.
This study has been carried out to find out the reasons for the wide variations observed in the correlation between serum and saliva lithium levels. Serum/saliva lithium levels were monitored in 10 individuals on 6 occasions. The correlation coefficient (r) varied within individuals from 0.19 to 0.91 (p less than 0.025) whereas when all the individuals were considered simultaneously, it was 0.59 (p less than 0.005). It was concluded that prediction of serum lithium levels from salivary lithium levels would only be possible in those individuals showing good correlation. The variability in this correlation could be mainly due to inter-individual variations in the particular sample of individuals studied.
开展本研究是为了找出血清锂水平与唾液锂水平之间相关性存在广泛差异的原因。对10名个体进行了6次血清/唾液锂水平监测。个体内部的相关系数（r）在0.19至0.91之间变化（p小于0.025），而当同时考虑所有个体时，相关系数为0.59（p小于0.005）。得出的结论是，只有在那些显示出良好相关性的个体中，才有可能根据唾液锂水平预测血清锂水平。这种相关性的变异性可能主要归因于所研究个体特定样本中的个体间差异。
