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儿童复杂性阑尾炎及其相关危险因素

Complicated appendicitis and associated risk factors among children.

作者信息

Azmeraw Molla, Abate Biruk Beletew, Temesgen Dessie, Feleke Sefineh Fenta, Haile Ribka Nigatu, Abate Melsew Dagne, Kitaw Tegene Atamenta

机构信息

Department of nursing, college of health science, Woldia University, Woldia, Ethiopia.

Department of epidemiology, college of health science, Woldia University, Woldia, Ethiopia.

出版信息

BMC Pediatr. 2025 Apr 29;25(1):336. doi: 10.1186/s12887-025-05447-5.

Abstract

BACKGROUND

Complicated appendicitis is one of significant pediatric surgical care challenges and its burden varied from 5 to 75%. However, there is limited study about prevalence of complicated appendicitis among children in Ethiopia. Therefore, this study aimed to assess the prevalence and associated factors of complicated appendicitis among children in Amhara region, Ethiopia.

METHODOLOGY

A cross-sectional study design was employed. The data extraction tool was used to collect data from 423 sampled participants. Simple random sampling technique was used. The data was presented using table, and text forms. The data was also summarized by proportion and frequency depends on the data type. The logistic model was fitted. Any statistical test considered significant at P-value < 0.05.

RESULT

A total of 406 study participants were included for analysis. The prevalence of complicated appendicitis was 32.02%, 95%CI(27.64%, 36.74%). Duration of symptom greater than 24 h, aOR = 1.64, 95% CI (1.01,2.66)), and white blood cell count greater than 12,000 cells/µl aOR = 2.08, 95% CI (1.15,3.77) were statistically significant predictors of complicated appendicitis in children.

CONCLUSION AND RECOMMENDATION

The prevalence of complicated appendicitis was high as compared to the previous studies. Patient presentation after 24 h of symptom and white blood cell greater than 12000 cells/µl were significantly associated with complicated appendicitis. The surgical teams need to be aware that those children with greater white blood cell count and a chief compliant duration of greater than one day were present with complicated appendicitis.

摘要

背景

复杂性阑尾炎是小儿外科护理面临的重大挑战之一,其发生率在5%至75%之间。然而,关于埃塞俄比亚儿童复杂性阑尾炎患病率的研究有限。因此,本研究旨在评估埃塞俄比亚阿姆哈拉地区儿童复杂性阑尾炎的患病率及其相关因素。

方法

采用横断面研究设计。使用数据提取工具从423名抽样参与者中收集数据。采用简单随机抽样技术。数据以表格和文本形式呈现。数据还根据数据类型按比例和频率进行汇总。拟合逻辑模型。任何P值<0.05的统计检验均被视为具有统计学意义。

结果

共纳入406名研究参与者进行分析。复杂性阑尾炎的患病率为32.02%,95%可信区间(27.64%,36.74%)。症状持续时间超过24小时,调整后比值比(aOR)=1.64,95%可信区间(1.01,2.66),白细胞计数大于12000个/微升,aOR=2.08,95%可信区间(1.15,3.77),是儿童复杂性阑尾炎的统计学显著预测因素。

结论与建议

与先前研究相比,复杂性阑尾炎的患病率较高。症状出现24小时后就诊以及白细胞计数大于12000个/微升与复杂性阑尾炎显著相关。手术团队需要意识到,白细胞计数较高且主要症状持续时间超过一天的儿童患有复杂性阑尾炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3f2/12039149/bf535149dd40/12887_2025_5447_Fig1_HTML.jpg

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