Chaker Kays, Tlili Syrine, Zehani Alia, Gharbia Nader, Snoussi Mariem, Frikha Wassim, Ghabi Hiba, Mosbahi Boutheina, Mami Ikram, Zouaghi Mohamed Karim, Nouira Yassine
Urology Department, La Rabta Hospital, BAB SAADOUN, 1006, Tunis, Tunisia.
Nephrology Department, La Rabta Hospital, Tunis, Tunisia.
J Med Case Rep. 2025 Apr 29;19(1):197. doi: 10.1186/s13256-025-05247-6.
The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension.
A 35-year-old African male patient referred to our institution, presenting with severe hypertension for 4 years. Renal magnetic resonance imaging showed a solid 9-mm lesion in the right upper pole cortex with high signal intensity on diffusion-weighted imaging, isointense on T2, and enhanced after contrast injection. The patient underwent an open right partial nephrectomy. The diagnosis of reninomas was confirmed by histopathological examination.
Nephron-sparing surgery should be considered in patients with juxtaglomerular tumors. This technique allows prompt recovery with the preservation of significant renal function.
该肿瘤产生过量肾素,导致继发性醛固酮增多症,从而引起伴有低钾血症的高血压。作者描述了一例年轻男性肾素瘤病例,该患者表现为恶性高血压。
一名35岁的非洲男性患者转诊至我院,有4年严重高血压病史。肾脏磁共振成像显示右肾上极皮质有一个9毫米的实性病灶,在扩散加权成像上呈高信号强度,T2加权像上等信号,注射造影剂后强化。患者接受了开放性右肾部分切除术。组织病理学检查确诊为肾素瘤。
对于肾小球旁器肿瘤患者,应考虑保留肾单位手术。该技术可使患者迅速康复,并保留显著的肾功能。