• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

立体定向放射治疗中小野剂量测定中不同小体积辐射探测器的比较与评估

Comparison and Assessment of Different Small Volume Radiation Detectors for Small Field Dosimetry in Stereotactic Radiotherapy.

作者信息

Dsouza Rechal Nisha, Sharan Krishna, Sukumar Suresh, Chandraguthi Srinidhi G, Rao Shreekripa, Lewis Shirley, Palaniappan Senthil Manikandan

机构信息

Department of Radiation Oncology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Department of Radiation Oncology, Justice K S Hegde Charitable Hospital, Deralakatte, Mangalore, Karnataka, India.

出版信息

Asian Pac J Cancer Prev. 2025 Apr 1;26(4):1343-1351. doi: 10.31557/APJCP.2025.26.4.1343.

DOI:10.31557/APJCP.2025.26.4.1343
PMID:40302087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12227971/
Abstract

OBJECTIVE

The small fields are used in the treatment of stereotactic radiosurgery (SRS), stereotactic radiotherapy (SRT), and stereotactic body radiation therapy (SBRT).  The aim of this study is to compare and assess various small-volume radiation detectors for small-field dosimetry.

METHODS

The small field dosimetry was performed with the High Definition Versa Linear Accelerator (HD-LINAC) from Elekta. The 6MV flattening filter (FF) and 6MV flattening filter free (FFF) radiation energies were chosen for the measurement.  The field sizes of 2x2cm2, 4x4cm2, 5x5cm2, 7x7cm2, 8x8cm2, and 10x10cm2 were selected. The quality assurance (QA) included percentage depth dose (PDD), dose profile measurement, and output factor (OF) measurement. The three radiation detectors, pinpoint ionization chamber type 31014, microDiamond detector type 60019, and Dosimetry diode SRS detector type 60018, from PTW-Freiburg, Germany, were utilized for the dosimetry. The measurements were performed with a radiation field analyzer (RFA) water phantom from PTW Freiburg.

RESULT

PDD values for all the detectors were similar except for Ds, which increased with the increase in field size in all detectors for the 6MV FF and 6MV FFF beams. Beam profile data gave similar results in all the detectors, with penumbra width having statistically significant differences in the 6MV FF beam between the three detectors. Penumbra width was found lower in pinpoint and microDiamond detectors for both energies compared to the SRS dosimetry diode.

CONCLUSION

The performance of all the detectors used in this study was similar with less noticeable differences between each other. As there was no great difference found in the results between the detectors, it can be concluded from this study that all three radiation detectors are suitable for the small field dosimetry performed for SRS and SBRT treatments.

摘要

目的

小射野用于立体定向放射外科治疗(SRS)、立体定向放射治疗(SRT)和立体定向体部放射治疗(SBRT)。本研究的目的是比较和评估用于小射野剂量测定的各种小体积辐射探测器。

方法

使用医科达公司的高清Versa直线加速器(HD-LINAC)进行小射野剂量测定。选择6MV均整滤过器(FF)和6MV无均整滤过器(FFF)的辐射能量进行测量。选择2×2cm²、4×4cm²、5×5cm²、7×7cm²、8×8cm²和10×10cm²的射野尺寸。质量保证(QA)包括百分深度剂量(PDD)、剂量分布测量和输出因子(OF)测量。使用德国PTW-弗莱堡公司生产的三种辐射探测器,即31014型针点电离室探测器、60019型微钻石探测器和60018型SRS剂量测定二极管探测器进行剂量测定。测量在PTW弗莱堡公司的射野分析仪(RFA)水模体上进行。

结果

除Ds外,所有探测器的PDD值相似,在6MV FF和6MV FFF射束下,所有探测器的Ds均随射野尺寸的增加而增加。所有探测器的射束分布数据结果相似,在6MV FF射束下,三种探测器之间的半值层宽度存在统计学显著差异。与SRS剂量测定二极管相比,两种能量下针点探测器和微钻石探测器的半值层宽度均较低。

结论

本研究中使用的所有探测器性能相似,彼此之间差异不明显。由于探测器之间的结果差异不大,因此本研究可以得出结论,所有三种辐射探测器都适用于SRS和SBRT治疗的小射野剂量测定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/414a7fb52a83/APJCP-26-1343-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/d252492fdc60/APJCP-26-1343-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/b18dee4fc928/APJCP-26-1343-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/ec7573167997/APJCP-26-1343-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/f922ae182c93/APJCP-26-1343-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/414a7fb52a83/APJCP-26-1343-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/d252492fdc60/APJCP-26-1343-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/b18dee4fc928/APJCP-26-1343-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/ec7573167997/APJCP-26-1343-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/f922ae182c93/APJCP-26-1343-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/12227971/414a7fb52a83/APJCP-26-1343-g005.jpg

相似文献

1
Comparison and Assessment of Different Small Volume Radiation Detectors for Small Field Dosimetry in Stereotactic Radiotherapy.立体定向放射治疗中小野剂量测定中不同小体积辐射探测器的比较与评估
Asian Pac J Cancer Prev. 2025 Apr 1;26(4):1343-1351. doi: 10.31557/APJCP.2025.26.4.1343.
2
Dosimetric investigation of small fields in radiotherapy measurements using Monte Carlo simulations, CC04 ionization chamber, and razor diode.使用蒙特卡罗模拟、CC04电离室和剃刀二极管对放射治疗测量中的小射野进行剂量学研究。
Phys Eng Sci Med. 2025 Jun 16. doi: 10.1007/s13246-025-01546-w.
3
Novel approach for determining beam latency using the center of mass of the radiation field measured with a diode detector array.使用二极管探测器阵列测量辐射场质心来确定射束延迟的新方法。
Z Med Phys. 2025 Jun 24. doi: 10.1016/j.zemedi.2025.06.001.
4
Efficacy of flattening-filter-free beam in stereotactic body radiation therapy planning and treatment: A systematic review with meta-analysis.立体定向体部放射治疗计划与治疗中无平板滤过器射束的疗效:一项荟萃分析的系统评价
J Med Imaging Radiat Oncol. 2017 Jun;61(3):379-387. doi: 10.1111/1754-9485.12583. Epub 2017 Jan 24.
5
A systematic review of the precision and accuracy of dose measurements in photon radiotherapy using polymer and Fricke MRI gel dosimetry.一项关于使用聚合物和弗里克磁共振成像凝胶剂量测定法进行光子放射治疗剂量测量的精度和准确性的系统综述。
Phys Med Biol. 2002 Oct 21;47(20):R107-21. doi: 10.1088/0031-9155/47/20/201.
6
Interventions for the treatment of brain radionecrosis after radiotherapy or radiosurgery.放疗或放射外科手术后脑放射性坏死的治疗干预措施。
Cochrane Database Syst Rev. 2018 Jul 9;7(7):CD011492. doi: 10.1002/14651858.CD011492.pub2.
7
Optimisation of chemotherapy and radiotherapy for untreated Hodgkin lymphoma patients with respect to second malignant neoplasms, overall and progression-free survival: individual participant data analysis.未治疗的霍奇金淋巴瘤患者化疗和放疗在第二原发性恶性肿瘤、总生存期和无进展生存期方面的优化:个体参与者数据分析
Cochrane Database Syst Rev. 2017 Sep 13;9(9):CD008814. doi: 10.1002/14651858.CD008814.pub2.
8
Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in adults and children aged 12 years and over.不同吸入性糖皮质激素及其与长效β2受体激动剂联合使用治疗12岁及以上成人和儿童慢性哮喘比较效果的系统评价与经济学分析
Health Technol Assess. 2008 May;12(19):iii-iv, 1-360. doi: 10.3310/hta12190.
9
Single and multitarget stereotactic radiosurgery (SRS) with single isocenter in the treatment of multiple brain metastases (BM): institutional experience.单中心单靶点及多靶点立体定向放射外科治疗多发脑转移瘤的机构经验
Clin Transl Oncol. 2025 Jan 15. doi: 10.1007/s12094-024-03844-3.
10
Sertindole for schizophrenia.用于治疗精神分裂症的舍吲哚。
Cochrane Database Syst Rev. 2005 Jul 20;2005(3):CD001715. doi: 10.1002/14651858.CD001715.pub2.

本文引用的文献

1
On dosimetric characteristics of detectors for relative dosimetry in small fields: a multicenter experimental study.用于小场相对剂量学的探测器剂量学特性:一项多中心实验研究。
Phys Med Biol. 2024 Jan 24;69(3). doi: 10.1088/1361-6560/ad154c.
2
Particular issues to be considered in small field dosimetry for TrueBeam STx commissioning.在 TrueBeam STx 调试中小野剂量学需要特别考虑的问题。
Appl Radiat Isot. 2023 Dec;202:111066. doi: 10.1016/j.apradiso.2023.111066. Epub 2023 Oct 14.
3
Small static radiosurgery field dosimetry with small volume ionization chambers.
使用小体积电离室进行小静态放射外科治疗野剂量测定。
Phys Med. 2022 May;97:66-72. doi: 10.1016/j.ejmp.2022.04.002. Epub 2022 Apr 13.
4
Characterization of a microSilicon diode detector for small-field photon beam dosimetry.用于小射束光子束剂量学的微硅二极管探测器的特性描述。
J Radiat Res. 2020 May 22;61(3):410-418. doi: 10.1093/jrr/rraa010.
5
Small-field dosimetry of TrueBeam flattened and flattening filter-free beams: A multi-institutional analysis.TrueBeam 平坦化和非平坦化过滤束的小射野剂量学:多机构分析。
J Appl Clin Med Phys. 2020 Jan;21(1):78-87. doi: 10.1002/acm2.12791. Epub 2019 Dec 9.
6
Detectors assessment for stereotactic radiosurgery with cones.用于立体定向放射外科手术的锥形探测器评估。
J Appl Clin Med Phys. 2018 Nov;19(6):88-98. doi: 10.1002/acm2.12449. Epub 2018 Sep 14.
7
Different Dosimeters/Detectors Used in Small-Field Dosimetry: Pros and Cons.小射野剂量学中使用的不同剂量仪/探测器:优缺点
J Med Signals Sens. 2018 Jul-Sep;8(3):195-203. doi: 10.4103/jmss.JMSS_3_18.
8
Output and ([Formula: see text]) correction factors measured and calculated in very small circular fields for microDiamond and EFD-3G detectors.在非常小的圆形射野中测量和计算的 microDiamond 和 EFD-3G 探测器的输出和[公式:见正文]校正因子。
Phys Med Biol. 2018 Jul 24;63(15):155002. doi: 10.1088/1361-6560/aacfb2.
9
Analysis of small field percent depth dose and profiles: Comparison of measurements with various detectors and effects of detector orientation with different jaw settings.小射野百分深度剂量及剂量分布分析:不同探测器测量结果的比较以及不同准直器设置下探测器方向的影响。
J Med Phys. 2016 Jan-Mar;41(1):12-20. doi: 10.4103/0971-6203.177284.
10
Evaluation of a synthetic single-crystal diamond detector for relative dosimetry measurements on a CyberKnife.在 CyberKnife 上进行相对剂量测量的合成单晶金刚石探测器的评估。
Br J Radiol. 2014 Mar;87(1035):20130768. doi: 10.1259/bjr.20130768.