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在 CyberKnife 上进行相对剂量测量的合成单晶金刚石探测器的评估。

Evaluation of a synthetic single-crystal diamond detector for relative dosimetry measurements on a CyberKnife.

机构信息

Radiotherapy Physics and Cancer Centre, Hall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK.

出版信息

Br J Radiol. 2014 Mar;87(1035):20130768. doi: 10.1259/bjr.20130768.

Abstract

OBJECTIVE

To evaluate a new commercial PTW-60019 microDiamond (PTW, Freiburg, Germany) synthetic single-crystal diamond detector for relative dosimetry measurements on a clinical CyberKnife™ VSI (Accuray Inc., Sunnyvale, CA) system.

METHODS

Relative output factors (ROFs) were measured for collimator diameters from 5 to 60 mm, and compared with diode [PTW-60017, PTW-60018 and IBA Dosimetry (Schwarzenbruck, Germany) SFD] and ionization chamber (PTW-31014 PinPoint and PTW-31010 Semiflex) measurements. Beam profiles were measured at a range of depths, and collimator sizes, with the detector stem oriented both parallel and perpendicular to the central axis (CAX). Percentage depth-dose (PDD) curves were obtained for the 60-mm collimator and compared with natural Diamond Detector (PTW-60003) and ionization chamber curves to evaluate energy dependence.

RESULTS

Penumbral broadening was noted on profile measurements made with the microDiamond oriented with the stem parallel to the CAX, in comparison with diodes. Oriented perpendicular to the CAX, the profile penumbra was sharper, but stem effects could not be ruled out. The PDD measurements were within 0.5% of ionization chamber measurements, indicating insignificant dose-rate dependence. The ROF for the microDiamond fell between diode and ionization chamber results. Published Monte Carlo-derived CyberKnife-specific factors were applied to the PTW-60017, PTW-60018 and PTW-31014 ROFs, and the microDiamond factors agreed within 2.0% of the mean of these.

CONCLUSION

Over a range of small field relative dosimetry measurements, the microDiamond detector shows excellent spatial resolution, dose-rate independence and water equivalence.

ADVANCES IN KNOWLEDGE

The microDiamond is a suitable tool for commissioning stereotactic systems.

摘要

目的

评估一种新的商用 PTW-60019 微金刚石(PTW,德国弗莱堡)合成单晶金刚石探测器,用于在临床 CyberKnife™ VSI(Accuray Inc.,加利福尼亚州桑尼维尔)系统上进行相对剂量测量。

方法

测量了从 5 到 60 毫米的准直器直径的相对输出因子(ROF),并与二极管[PTW-60017、PTW-60018 和 IBA 剂量学(施瓦茨布鲁克,德国)SFD]和电离室(PTW-31014 PinPoint 和 PTW-31010 Semiflex)测量进行了比较。在一系列深度和准直器尺寸下测量了束流轮廓,探测器柄平行和垂直于中央轴(CAX)两种方向。获得了 60 毫米准直器的百分深度剂量(PDD)曲线,并与天然金刚石探测器(PTW-60003)和电离室曲线进行比较,以评估能量依赖性。

结果

与二极管相比,当微金刚石的柄平行于 CAX 定向时,在轮廓测量中观察到半影展宽。当垂直于 CAX 定向时,轮廓半影更清晰,但不能排除柄的影响。PDD 测量与电离室测量相差 0.5%以内,表明剂量率依赖性不明显。微金刚石的 ROF 介于二极管和电离室结果之间。将蒙特卡罗衍生的特定于 CyberKnife 的特定因素应用于 PTW-60017、PTW-60018 和 PTW-31014 的 ROF,微金刚石因素与这些因素的平均值相差在 2.0%以内。

结论

在小范围的相对剂量测量中,微金刚石探测器显示出出色的空间分辨率、剂量率独立性和水等效性。

知识进步

微金刚石是用于立体定向系统调试的合适工具。

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