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[大鼠中ω-鼠胆酸的形成及胆汁酸的粪便排泄]

[Formation of omega-muricholic acid and fecal excretion of biliary acids in rats].

作者信息

Sacquet E, Leprince C, Riottot M, Méjan C, Léglise P

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Feb 14;284(7):557-9.

PMID:403022
Abstract

Two groups of Rats which were fed the same diet, excreted fecal bile acids of different patterns: in one group, the feces contained a large amount of omega-muricholic acid and very little hydrodeoxycholic acid; in the other group the reversed composition was observed. The first group excreted more total bile acids than the second. This observation suggests that the formation of a large amount of omega-muricholic acid results in an increase in total bile acid fecal excretion.

摘要

两组喂食相同饮食的大鼠排出的粪便胆汁酸模式不同

一组粪便中含有大量的ω-鼠胆酸,而猪去氧胆酸含量很少;另一组则观察到相反的成分。第一组排出的总胆汁酸比第二组多。这一观察结果表明,大量ω-鼠胆酸的形成导致粪便中总胆汁酸排泄增加。

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