Mentzel Luise, Fengler Karl, Oezkur Mehmet, Lanmüller Pia, Tavazzi Guido, Thevathasan Tharusan, Iannaccone Mario, Werner Nikos
Department of Cardiology, Heart Center Leipzig, University of Leipzig, Strümpellstraße 39, Leipzig 04289, Germany.
Department of Cardiovascular Surgery, University Hospital of Mainz, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeck straße 1, Mainz 55131, Germany.
Eur Heart J Suppl. 2025 Feb 4;27(Suppl 4):iv47-iv54. doi: 10.1093/eurheartjsupp/suaf001. eCollection 2025 Apr.
Acute pulmonary embolism (PE) is a life-threatening condition caused by the thrombo-embolic obstruction of pulmonary arteries, which often leads to haemodynamic instability, right ventricular failure, and potentially death. Patients with massive or high-risk PE are particularly vulnerable and may not respond to conventional treatments, necessitating the implementation of mechanical circulatory support. Here, we discuss recent advancements in the diagnosis and multidisciplinary management of patients with high-risk PE and highlight the need for rapid and personalized treatment strategies.
急性肺栓塞（PE）是一种由肺动脉血栓栓塞性阻塞引起的危及生命的疾病，常导致血流动力学不稳定、右心室衰竭，并可能导致死亡。大面积或高危PE患者尤其脆弱，可能对传统治疗无反应，因此需要实施机械循环支持。在此，我们讨论高危PE患者诊断和多学科管理的最新进展，并强调快速和个性化治疗策略的必要性。
