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Mechanometabolic Regulation in Cancer Progression: Lessons from Fibrotic Remodeling.

作者信息

Wen Chen-Yueh, Chen Po-Hung, Chang Renin, Yong Su-Boon, Yii Chin-Yuan, Chin Yen, Li Chia-Jung

机构信息

Division of Urology, Show Chwan Memorial Hospital, Changhua 500, Taiwan.

Department of Emergency Medicine, Kaohsiung Municipal Min-Sheng Hospital, Kaohsiung 802, Taiwan.

出版信息

Int J Biol Sci. 2025 Mar 31;21(6):2672-2675. doi: 10.7150/ijbs.112325. eCollection 2025.

DOI:10.7150/ijbs.112325
PMID:40303306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12035907/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128d/12035907/9f4b0592c997/ijbsv21p2672g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128d/12035907/9f4b0592c997/ijbsv21p2672g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128d/12035907/9f4b0592c997/ijbsv21p2672g001.jpg

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J Immunother Cancer. 2025 Jan 16;13(1):e010540. doi: 10.1136/jitc-2024-010540.
2
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.TAGLN-RhoA/ROCK2-SLC2A3介导的机械代谢轴促进皮肤纤维化。
Int J Biol Sci. 2025 Jan 1;21(2):658-670. doi: 10.7150/ijbs.104484. eCollection 2025.
3
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
DNMT1驱动的RORA甲基化通过SLC2A3促进缺氧条件下食管鳞状细胞癌的进展。
J Transl Med. 2024 Dec 31;22(1):1167. doi: 10.1186/s12967-024-05960-8.
4
Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells.Glut3 促进 Treg 细胞的细胞 O-GlcNAcylation，这是 Treg 细胞的一个独特的肿瘤支持特征。
Cell Mol Immunol. 2024 Dec;21(12):1474-1490. doi: 10.1038/s41423-024-01229-8. Epub 2024 Oct 28.
5
Neurodevelopment Is Dependent on Maternal Diet: Placenta and Brain Glucose Transporters GLUT1 and GLUT3.神经发育依赖于母体饮食：胎盘和大脑葡萄糖转运蛋白 GLUT1 和 GLUT3。
Nutrients. 2024 Jul 21;16(14):2363. doi: 10.3390/nu16142363.
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SIRT7 knockdown promotes gemcitabine sensitivity of pancreatic cancer cell via upregulation of GLUT3 expression.SIRT7 knockdown 通过上调 GLUT3 表达促进胰腺癌细胞对吉西他滨的敏感性。
Cancer Lett. 2024 Aug 28;598:217109. doi: 10.1016/j.canlet.2024.217109. Epub 2024 Jul 17.
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Glucose transporter 3 in neuronal glucose metabolism: Health and diseases.神经元葡萄糖代谢中的葡萄糖转运蛋白3：健康与疾病
Metabolism. 2021 Oct;123:154869. doi: 10.1016/j.metabol.2021.154869. Epub 2021 Aug 21.