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伊斯法罕一家转诊心脏病医院收治患者低镁血症患病率及相关危险因素评估

Evaluation of the Prevalence of Hypomagnesemia and the Related Risk Factors in Patients Admitted to a Referral Heart Hospital in Isfahan.

作者信息

Soudmandi Mahdi, Dianatkhah Mehrnoush, Momenzadeh Mahnaz, Teimouri-Jervekani Zahra

机构信息

Department of Clinical Pharmacy and Pharmacy Practice, Isfahan University of Medical Sciences, Isfahan, Iran.

Student Research Committee, Pharmacy Faculty, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2025 Mar 28;14:25. doi: 10.4103/abr.abr_106_24. eCollection 2025.

Abstract

BACKGROUND

Magnesium is one of the most abundant cations in the body and plays a vital role in the function of the cardiovascular system. Hypomagnesemia can cause severe and dangerous cardiovascular complications. Also, since drugs that can lead to hypomagnesemia are commonly prescribed to cardiac patients, we decided to investigate the prevalence of hypomagnesemia in the population of cardiac patients to be aware of the prevalence of this condition as an important risk factor for cardiovascular events.

MATERIALS AND METHODS

This study is a retrospective cross-sectional study of an analytical-observational type with a fundamental-applied approach, in which by recording the information of patients in pre-designed forms, the prevalence of hypomagnesemia in them and also the prevalence of hypomagnesemia separation of different heart diseases and the relationship of hypomagnesemia with age, sex, glomerular filtration rate (GFR), and drugs used have been evaluated.

RESULTS

A total of 982 patients were included in the study, of which 636 were men and 346 were women. The average age of the patients in this study was 63 years. Hypomagnesemia was observed in 138 patients (14%), and the prevalence of hypomagnesemia in patients with ventricular arrhythmias was 40%. It was also observed that only 47% of the patients with hypomagnesemia received magnesium, and the rest were not treated.

CONCLUSION

This study highlights the importance of magnesium status and its relationship with various clinical factors in the studied population. This emphasizes the need to increase attention to hypomagnesemia, especially among vulnerable groups such as women and older adults.

摘要

背景

镁是人体中含量最丰富的阳离子之一,在心血管系统功能中起着至关重要的作用。低镁血症可导致严重且危险的心血管并发症。此外,由于常用于心脏病患者的药物可能会导致低镁血症,我们决定调查心脏病患者群体中低镁血症的患病率,以便了解这种情况作为心血管事件重要危险因素的流行程度。

材料与方法

本研究是一项采用基础 - 应用方法的分析性观察性回顾性横断面研究,通过以预先设计的表格记录患者信息,评估了他们中低镁血症的患病率、不同心脏病中低镁血症的患病率以及低镁血症与年龄、性别、肾小球滤过率(GFR)和所用药物之间的关系。

结果

本研究共纳入982例患者,其中男性636例,女性346例。本研究中患者的平均年龄为63岁。138例患者(14%)出现低镁血症,室性心律失常患者中低镁血症的患病率为40%。还观察到,只有47%的低镁血症患者接受了镁补充治疗,其余患者未接受治疗。

结论

本研究强调了镁状态及其与研究人群中各种临床因素关系的重要性。这突出了需要更多关注低镁血症,尤其是在女性和老年人等弱势群体中。

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本文引用的文献

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Association of hypomagnesemia with cardiovascular diseases and hypertension.低镁血症与心血管疾病和高血压的关联。
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