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2021年中国西北部出现高致病性禽流感（H5N8）病毒。

Emerging Highly Pathogenic Avian Influenza (H5N8) Virus in in Northwest China in 2021.

作者信息

He Zhen, Jin Tiezhi, Wu Weikang, Zhao Zhe, Lu Zhenhua, Song Shuxuan, Liu Kun, Shao Zhongjun

机构信息

Department of Epidemiology, School of Public Health, Air Force Medical University, Xi'an 710032, China.

Shaanxi Institute of Zoology, Xi'an 710032, China.

出版信息

Transbound Emerg Dis. 2023 Feb 21;2023:7896376. doi: 10.1155/2023/7896376. eCollection 2023.

DOI:10.1155/2023/7896376
PMID:40303702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12017185/
Abstract

Three highly pathogenic avian influenza (H5N8) viruses were detected in the migratory bird in Northwest China in June 2021. Phylogenetic analysis indicated that these H5N8 isolates belonged to clade 2.3.4.4b, which were highly homologous to strains isolated in China and South Korea. In this study, H5N8 virus infection in was detected using Oxford Nanopore Technologies sequencing technology and caused pathological changes in multiple organs.

摘要

2021年6月，在中国西北部的候鸟中检测到三种高致病性禽流感（H5N8）病毒。系统发育分析表明，这些H5N8分离株属于2.3.4.4b分支，与在中国和韩国分离的毒株高度同源。在本研究中，使用牛津纳米孔技术测序技术检测到H5N8病毒感染，并在多个器官中引起了病理变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/faa28cc495f0/TBED2023-7896376.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/e78d67a53431/TBED2023-7896376.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/d9ebc736596a/TBED2023-7896376.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/faa28cc495f0/TBED2023-7896376.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/e78d67a53431/TBED2023-7896376.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/d9ebc736596a/TBED2023-7896376.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a285/12017185/faa28cc495f0/TBED2023-7896376.003.jpg

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本文引用的文献

1
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Emerg Microbes Infect. 2022 Dec;11(1):73-82. doi: 10.1080/22221751.2021.2011622.
2
Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China.全球流行的 H5N8 禽流感病毒的遗传和生物学特性，以及中国目前使用的家禽疫苗提供的保护效果。
Sci China Life Sci. 2022 Apr;65(4):795-808. doi: 10.1007/s11427-021-2025-y. Epub 2021 Nov 8.
3
Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020.
2020 年中国中部候鸟中出现的高致病性禽流感（H5N8）病毒。
Emerg Microbes Infect. 2021 Dec;10(1):1503-1506. doi: 10.1080/22221751.2021.1956372.
4
Emerging H5N8 avian influenza viruses.新出现的H5N8禽流感病毒
Science. 2021 May 21;372(6544):784-786. doi: 10.1126/science.abg6302.
5
Evolution and extensive reassortment of H5 influenza viruses isolated from wild birds in China over the past decade.过去十年中在中国野生鸟类中分离的 H5 流感病毒的进化和广泛重配。
Emerg Microbes Infect. 2020 Dec;9(1):1793-1803. doi: 10.1080/22221751.2020.1797542.
6
Minimap2: pairwise alignment for nucleotide sequences.Minimap2：核苷酸序列的两两比对。
Bioinformatics. 2018 Sep 15;34(18):3094-3100. doi: 10.1093/bioinformatics/bty191.
7
Human infection with a novel, highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings.人感染新型高致病性禽流感 A（H5N6）病毒：病毒学和临床发现。
J Infect. 2016 Jan;72(1):52-9. doi: 10.1016/j.jinf.2015.06.009. Epub 2015 Jul 2.
8
Novel Eurasian highly pathogenic avian influenza A H5 viruses in wild birds, Washington, USA, 2014.2014年美国华盛顿野生鸟类中出现的新型欧亚高致病性甲型H5禽流感病毒
Emerg Infect Dis. 2015 May;21(5):886-90. doi: 10.3201/eid2105.142020.
9
Intercontinental Spread of Asian-Origin H5N8 to North America through Beringia by Migratory Birds.亚洲起源的H5N8通过候鸟经白令陆桥向北美洲际传播。
J Virol. 2015 Jun;89(12):6521-4. doi: 10.1128/JVI.00728-15. Epub 2015 Apr 8.
10
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Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):172-7. doi: 10.1073/pnas.1405216112. Epub 2014 Dec 22.