Goff D C, Garber H J, Jenike M A
J Clin Psychiatry. 1985 Sep;46(9):400-1.
A healthy 25-year-old woman experienced probable ranitidine-induced confusion that partially resolved with intravenous physostigmine. The only known prior report of confusion associated with this relatively new agent was in a severely ill 86-year-old woman. Clinicians should be alert for mental status changes with ranitidine and consider a trial of physostigmine when indicated.
一名25岁健康女性经历了可能由雷尼替丁引起的意识混乱,静脉注射毒扁豆碱后症状部分缓解。此前关于这种相对较新药物导致意识混乱的唯一已知报告是在一名86岁重症女性身上。临床医生应警惕雷尼替丁引起的精神状态变化,并在有指征时考虑试用毒扁豆碱。