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小儿严重过敏反应治疗后的神经认知表现。

Neurocognitive manifestation after treatment of pediatric severe anaphylaxis.

作者信息

Nti Benjamin, Allen Sheryl

机构信息

Indiana University School of Medicine, Indianapolis, Indiana, 46202, USA.

Eli Lilly Company, Indianapolis, Indiana, USA.

出版信息

BMC Neurol. 2025 Apr 30;25(1):192. doi: 10.1186/s12883-025-04177-6.

Abstract

BACKGROUND

Anaphylaxis is a common, severe, and life-threatening allergic reaction that occurs rapidly after exposure to an allergen which can affect multiple systems in the body. In rare cases, it may lead to additional neurological manifestations that are poorly understood.

CASE PRESENTATION

We present a case of a 14-year-old boy who experienced severe anaphylaxis necessitating airway intervention and admission to critical care. While his initial presentation and treatment aligned with current standards, he subsequently developed prolonged neurological deficits, including weakness, prosopagnosia, amnesia, and loss of basic functions, during an extended recovery period.

CONCLUSION

This rare neurological manifestation following anaphylaxis may be overlooked by many clinicians. Therefore, it is imperative to highlight this potential complication to improve the management of patients experiencing anaphylaxis.

摘要

背景

过敏反应是一种常见、严重且危及生命的过敏反应,接触过敏原后迅速发生,可影响身体多个系统。在罕见情况下,它可能导致尚不十分清楚的其他神经学表现。

病例介绍

我们报告一例14岁男孩,他经历了严重过敏反应,需要气道干预并入住重症监护病房。虽然他的初始表现和治疗符合现行标准,但在延长的恢复期,他随后出现了长期神经功能缺损,包括虚弱、面孔失认症、失忆以及基本功能丧失。

结论

许多临床医生可能会忽略过敏反应后这种罕见的神经学表现。因此,必须强调这种潜在并发症,以改善对过敏反应患者的管理。

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