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通过后路进行颈椎小关节靶向性前路扩张可实现间接椎间孔减压并减轻椎体滑脱:一项尸体研究

Targeted anterior expansion of the cervical facet joints achieves indirect foraminal decompression and reduces spondylolisthesis via a posterior approach: a cadaveric study.

作者信息

Al-Habib Amro, AlEissa Sami, Al-Jazaeri Ayman

机构信息

Division of Neurosurgery, Department of Surgery, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.

Department of Orthopedics, King Abdulaziz Medical City and King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

出版信息

J Orthop Surg Res. 2025 May 1;20(1):437. doi: 10.1186/s13018-025-05851-8.

DOI:10.1186/s13018-025-05851-8
PMID:40307884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12044982/
Abstract

BACKGROUND

In this cadaveric study, we aimed to assess the effects of distraction at the anterior end of the cervical facet joints (CFJ), achieved via a posterior cervical approach (PCA), on intervertebral neural foraminal height (IVFH) and segmental alignment. A novel cervical expandable facet implant (CeLFI) was used to facilitate anterior expansion within the CFJ.

METHODS

This study was conducted in three time periods (2018, 2019, and 2024). The CeLFI was primarily placed at the CSPL levels or at the non-fused C3-7 levels if no CSPL was present. Pre- and post-implantation outcomes were assessed using cervical spine radiography and computed tomography (CT) scan. Changes in facet joint space (FJS) height, IVFH, interspinous distance (ISD), intervertebral disc height (IVDH), and cervical alignment were assessed.

RESULTS

CeLFI insertion (n = 12) resulted in an increase in the mean IVFH (+ 1.5 mm left; + 2 mm right, both p < 0.001), FJS height (+ 2.41 mm left; 2.53 mm right, both p < 0.001), ISD (+ 2.83 mm, p = 0.003), and posterior IVDH (+ 1.16 mm p = 0.001). In the cadavers with CSPL (n = 9), a segmental reduction was observed, which remained stable in flexion-extension radiographs. Two cadavers also showed unbuckling of the posterior interspinous ligaments on post-insertion CT. No significant changes in overall cervical alignment were observed after CeLFI insertion.

CONCLUSIONS

Indirect cervical intervertebral foraminal decompression and reduction of cervical segmental spondylolisthesis were achieved via a PCA with targeted distraction at the anterior end of the CFJ. This novel concept is promising but requires further clinical studies to evaluate its benefit for patients with degenerative cervical spine disease.

摘要

背景

在这项尸体研究中,我们旨在评估通过后路颈椎入路(PCA)在颈椎小关节(CFJ)前端进行撑开对椎间孔高度(IVFH)和节段对线的影响。使用一种新型的颈椎可扩张小关节植入物(CeLFI)来促进CFJ内的前方扩张。

方法

本研究分三个时间段(2018年、2019年和2024年)进行。如果不存在CSPL,CeLFI主要放置在CSPL水平或未融合的C3 - 7水平。使用颈椎X线摄影和计算机断层扫描(CT)评估植入前和植入后的结果。评估小关节间隙(FJS)高度、IVFH、棘突间距离(ISD)、椎间盘高度(IVDH)和颈椎对线的变化。

结果

插入CeLFI(n = 12)导致平均IVFH增加(左侧增加1.5毫米;右侧增加2毫米,p均<0.001),FJS高度增加(左侧增加2.41毫米;右侧增加2.53毫米,p均<0.001),ISD增加(增加2.83毫米,p = 0.003),以及后方IVDH增加(增加1.16毫米,p = 0.001)。在有CSPL的尸体(n = 9)中,观察到节段性复位,在屈伸位X线片上保持稳定。两具尸体在植入后CT上还显示棘突间后韧带松开。插入CeLFI后未观察到颈椎整体对线有显著变化。

结论

通过PCA在CFJ前端进行靶向撑开,实现了间接颈椎椎间孔减压和颈椎节段性椎体滑脱的复位。这一新概念很有前景,但需要进一步的临床研究来评估其对退行性颈椎疾病患者的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/40100fa82ae5/13018_2025_5851_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/e655601878fa/13018_2025_5851_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/6788e89c783c/13018_2025_5851_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/6c5b8e67a11d/13018_2025_5851_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/7fced9d4c7c7/13018_2025_5851_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/40100fa82ae5/13018_2025_5851_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/e655601878fa/13018_2025_5851_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/6788e89c783c/13018_2025_5851_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/6c5b8e67a11d/13018_2025_5851_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/7fced9d4c7c7/13018_2025_5851_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc55/12044982/40100fa82ae5/13018_2025_5851_Fig6_HTML.jpg

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