Lothe K, Spycher M A, Rüttner J R
J Bone Joint Surg Br. 1985 Aug;67(4):543-7. doi: 10.1302/0301-620X.67B4.4030847.
Human articular cartilage taken from 92 femoral heads at autopsy was examined macroscopically and microscopically. Fifty-two showed no changes except for occasional slight degeneration in the non-pressure areas; these changes were visible only microscopically. In the remaining 40 heads, different degrees of osteoarthrosis were seen; half the heads also showed focal lacunar resorptive lesions in the cartilage. The origin of this focal cartilage resorption is discussed and its possible association with necrosis, pannus formation and enzymatic synovial activities. We conclude that there is no evidence of a direct relationship between focal cartilage resorption and osteoarthrosis.
对92个取自尸检股骨头的人类关节软骨进行了宏观和微观检查。52个样本除了在非压力区域偶尔出现轻微退变外无其他变化；这些变化仅在显微镜下可见。在其余40个股骨头中，可见不同程度的骨关节炎；半数股骨头的软骨中还出现了局灶性陷窝吸收性病变。本文讨论了这种局灶性软骨吸收的起源及其与坏死、血管翳形成和滑膜酶活性的可能关联。我们得出结论，没有证据表明局灶性软骨吸收与骨关节炎之间存在直接关系。
