埃塞俄比亚东北部康博尔查都市行政镇育龄妇女异常子宫出血的发生率及影响因素：一项基于FIGO的研究（2023年）

Magnitude and determinants of abnormal uterine bleeding among reproductive-age women in Kombolcha Rejiopolitan Administrative Town, Northeast Ethiopia: a FIGO-based study (2023).

作者信息

Seid Abubeker, Bulto Gizachew Abdissa, Yesuf Adem, Yimer Ali, Ahmed Hassen, Muse Tsegaye Benti

机构信息

Department of Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia.

Department of Midwifery, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.

出版信息

Front Reprod Health. 2025 Apr 16;7:1559105. doi: 10.3389/frph.2025.1559105. eCollection 2025.

DOI:10.3389/frph.2025.1559105

PMID:40308485

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12040982/

Abstract

BACKGROUND

Abnormal uterine bleeding (AUB) is a common reason for women to seek healthcare, affecting their health, quality of life, productivity, and increasing the risk of complications. While menstrual disorders have been studied in Ethiopia, the prevalence and determinants of AUB among reproductive-age women remain poorly understood due to the use of outdated terminology and a lack of standardized approaches, which hinder accurate assessment and comparison with international findings. This study aims to address this gap by assessing the magnitude and determinants of AUB among reproductive-age women in Kombolcha town, Ethiopia, using the 2018 FIGO criteria.

METHODS

A community-based cross-sectional study was conducted among 608 reproductive-age women in Kombolcha town from April 20 to May 20, 2023, using systematic random sampling. Data were collected using interviewer-administered structured questionnaires. The data were entered into EPI Data version 4.6 and analyzed using SPSS version 26. All predictor variables with a -value <0.25 in bivariable analysis were included in multivariable logistic regression. Variables with a -value <0.05 in the multivariable analysis were considered statistically significant predictors of abnormal uterine bleeding.

RESULT

This study found that 36.5% of 591 reproductive-age women experienced abnormal uterine bleeding (AUB). Several factors were significantly associated with AUB: Women in late reproductive age (41-49 years) had 4.2 times higher odds of experiencing AUB compared to those in mid-reproductive age (AOR = 4.181, 95% CI: 2.199-7.948). Hypertensive women were 3.71 times more likely to experience AUB (AOR = 3.706, 95% CI: 1.106-12.417). Women with a history of abortion had 2.3 times higher odds of AUB (AOR = 2.345, 95% CI: 1.069-5.147). A history of diagnosed anemia and late menarche (≥15 years) were also significantly associated with increased AUB risk (AOR = 2.939, 95% CI: 1.437-6.010; AOR = 3.824, 95% CI: 2.199-7.948).

CONCLUSION

This study highlights the significant burden of AUB, with 36.5% of women affected. Healthcare providers should educate patients about lifestyle changes, treatment options, and when to seek emergency care for AUB to improve health outcomes.

摘要

背景

异常子宫出血（AUB）是女性寻求医疗保健的常见原因，影响她们的健康、生活质量、生产力，并增加并发症风险。虽然埃塞俄比亚对月经紊乱进行了研究，但由于使用过时的术语以及缺乏标准化方法，育龄妇女中AUB的患病率和决定因素仍知之甚少，这阻碍了准确评估以及与国际研究结果的比较。本研究旨在通过使用2018年FIGO标准评估埃塞俄比亚孔博尔查镇育龄妇女中AUB的严重程度和决定因素来填补这一空白。

方法

2023年4月20日至5月20日，在孔博尔查镇608名育龄妇女中进行了一项基于社区的横断面研究，采用系统随机抽样。通过访员管理的结构化问卷收集数据。数据录入EPI Data 4.6版本，并使用SPSS 26版本进行分析。在双变量分析中P值<0.25的所有预测变量都纳入多变量逻辑回归。多变量分析中P值<0.05 的变量被认为是异常子宫出血的统计学显著预测因素。

结果

本研究发现，591名育龄妇女中有36.5%经历过异常子宫出血（AUB）。几个因素与AUB显著相关：晚育年龄（41 - 49岁）的女性经历AUB的几率比中年育龄女性高4.2倍（调整后比值比[AOR]=4.181，95%置信区间[CI]：2.199 - 7.948）。高血压女性经历AUB的可能性高3.71倍（AOR = 3.706，95% CI：1.106 - 12.417）。有流产史的女性发生AUB的几率高2.3倍（AOR = 2.345，95% CI：1.069 - 5.147）。诊断为贫血和初潮晚（≥15岁）的病史也与AUB风险增加显著相关（AOR = 2.939，95% CI：1.437 - 6.010；AOR = 3.824，95% CI：2.199 - 7.948）。