摇蚊唾液腺中的一种新型巨大分泌多肽：对另一个巴尔比亚尼环基因的启示。
A novel giant secretion polypeptide in Chironomus salivary glands: implications for another Balbiani ring gene.
作者信息
Kao W Y, Case S T
出版信息
J Cell Biol. 1985 Sep;101(3):1044-51. doi: 10.1083/jcb.101.3.1044.
Abstract
Chironomus salivary glands contain a family of high Mr (approximately 1,000 X 10(3)) secretion polypeptides thought to consist of three components: sp-Ia, sp-Ib, and sp-Ic. The use of a new extraction protocol revealed a novel high Mr component, sp-Id. Results of a survey of individual salivary glands indicated that sp-Id was widespread in more than a dozen strains of C. tentans and C. pallidivittatus. Sp-Id was phosphorylated at Ser residues, and a comparison of cyanogen bromide and tryptic peptide maps of 32P-labeled polypeptides suggested that sp-Ia, sp-Ib, and sp-Id are comprised of similar but nonidentical tandemly repeated amino acid sequences. We concluded that sp-Id is encoded by an mRNA whose size and nucleotide sequence organization are similar to Balbiani ring (BR) mRNAs that code for the other sp-I components. Furthermore, parallel repression of sp-Ib and sp-Id synthesis by galactose led us to hypothesize that both of their genes exist within Balbiani ring 2.
摘要
摇蚊唾液腺含有一族高分子量（约1000×10³）的分泌多肽，被认为由三个组分组成：sp-Ia、sp-Ib和sp-Ic。一种新提取方案的应用揭示了一种新的高分子量组分，sp-Id。对单个唾液腺的调查结果表明，sp-Id广泛存在于十几种细摇蚊和苍白摇蚊品系中。Sp-Id在丝氨酸残基处被磷酸化，对32P标记多肽的溴化氰和胰蛋白酶肽图的比较表明，sp-Ia、sp-Ib和sp-Id由相似但不相同的串联重复氨基酸序列组成。我们得出结论，sp-Id由一种mRNA编码，其大小和核苷酸序列组织与编码其他sp-I组分的巴尔比亚尼环（BR）mRNA相似。此外，半乳糖对sp-Ib和sp-Id合成的平行抑制使我们推测它们的基因都存在于巴尔比亚尼环2内。
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A novel giant secretion polypeptide in Chironomus salivary glands: implications for another Balbiani ring gene.摇蚊唾液腺中的一种新型巨大分泌多肽：对另一个巴尔比亚尼环基因的启示。
J Cell Biol. 1985 Sep;101(3):1044-51. doi: 10.1083/jcb.101.3.1044.
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本文引用的文献
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Balbiani ring induction in phosphate metabolism.磷酸盐代谢中的巴尔比安尼环诱导。
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Evidence for a common ancestor sequence for the Balbiani ring 1 and Balbiani ring 2 genes in Chironomus tentans.证据表明，在摇蚊 Chironomus tentans 中，巴尔比尼环 1 和巴尔比尼环 2 基因存在共同的祖先序列。
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The Balbiani ring 2 gene in Chironomus tentans is built from two types of tandemly arranged major repeat units with a common evolutionary origin.摇蚊中的 Balbiani 环 2 基因由两种具有共同进化起源的串联排列的主要重复单位构建而成。
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Constant and variable parts in the Balbiani ring 2 repeat unit and the translation termination region.巴尔比尼环 2 重复单元和翻译终止区的恒变部分。
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[RIBONUCLEIC ACID SYNTHESIS IN GIANT CHROMOSOMES. AUTORADIOGRAPHIC INVESTIGATIONS ON CHIRONOMUS TENTANS].[巨染色体中的核糖核酸合成。摇蚊的放射自显影研究]
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[Cytological analysis of a Camptochironomus hybrid species. I. Results of crossing and development of the karyotype].[一种摇蚊杂交物种的细胞学分析。I. 杂交结果与核型发育]
Chromosoma. 1955;7(2-3):198-259. doi: 10.1007/BF00329725.
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Large sized nascent protein as dominating component during protein synthesis in Chironomus salivary glands.大型新生蛋白是摇蚊唾液腺蛋白质合成过程中的主要成分。
Chromosoma. 1980;81(1):85-99. doi: 10.1007/BF00292424.
8
Concomitant induction of a Balbiani ring and a giant secretory protein in Chironomus salivary glands.摇蚊唾液腺中巴尔比亚尼环和一种巨大分泌蛋白的伴随诱导。
Chromosoma. 1980;81(1):115-24. doi: 10.1007/BF00292426.
9
Sequences translated by Balbiani ring 75S RNA in vitro are present in giant secretory protein from Chironomus tentans.由摇蚊75S RNA在体外翻译的序列存在于摇蚊的巨大分泌蛋白中。
Chromosoma. 1980;81(1):101-13. doi: 10.1007/BF00292425.
10
Modulation of 75S RNA synthesis in the Balbiani rings of Chironomus tentans with galactose treatment.用半乳糖处理对摇蚊唾腺巴尔比亚尼环中75S RNA合成的调控
Chromosoma. 1981;83(5):645-59. doi: 10.1007/BF00328524.
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