针对血支原体（血原虫）的“同一健康”方法：巴西社区及其犬类中的分子检测
One Health approach to hemotropic mycoplasmas (hemoplasmas): Molecular detection in communities and their dogs in Brazil.
作者信息
Kmetiuk Louise Bach, Shaw Paul, Wallington Ashley, Panazzolo Giovanni Kalempa, Domingues Orlei José, Kattoor Jobin Jose, Johnson Mathew, Biondo Lendro Meneguelli, Wilkes Rebecca, Figueiredo Fabiano Borges, Fávero Giovani Marino, Messick Joanne B, Dos Santos Andrea Pires, Biondo Alexander Welker
机构信息
Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States of America.
Carlos Chagas Institute, Oswaldo Cruz Foundation, Curitiba, PR, Brazil.
出版信息
One Health. 2025 Mar 29;20:101024. doi: 10.1016/j.onehlt.2025.101024. eCollection 2025 Jun.
Hemoplasmas (hemotropic mycoplasmas) are obligatory red blood cell bacteria that may infect and cause anemia in several mammalian species. IAccordingly, the present study assessed four quilombola communities during six on-field expeditions between December 2021 and March 2022 in the central-eastern Paraná State, southern Brazil. Overall, 12/208 (5.8 %) quilombola individuals were positive for hemoplasma infection by qPCR. Results of 16S ribosomal RNA gene sequencing confirmed Mycoplasma heamocanis infection in two human samples. In addition, hemoplasma infection was detected by qPCR in 19/100 (19.0 %) dogs including 16/19 (84.2 %) dogs for Candidatus Mycoplasma haematoparvum, 7/19 (3.7 %) for , and 4/19 (21.0 %) for both. To the author's knowledge, this is the first One Health approach study of hemoplasma detection in quilombola individuals along with their dogs as vulnerable populations worldwide, with M. heamocanis detection in both human and companion animals.
血支原体（嗜血性支原体）是一类专性寄生于红细胞内的细菌，可感染多种哺乳动物并导致贫血。因此，本研究于2021年12月至2022年3月期间，在巴西南部巴拉那州中东部地区的六次实地考察中，对四个基隆博社区进行了评估。总体而言，通过定量聚合酶链反应（qPCR）检测，208名基隆博社区居民中有12人（5.8%）血支原体感染呈阳性。16S核糖体RNA基因测序结果证实，两份人类样本感染了犬血支原体。此外，通过qPCR检测发现，100只狗中有19只（19.0%）感染了血支原体，其中19只感染犬细小血支原体相关菌（Candidatus Mycoplasma haematoparvum）的狗中有16只（84.2%），感染[此处原文缺失具体菌种名称]的有7只（3.7%），同时感染两种的有4只（21.0%）。据作者所知，这是首次在全球范围内，以“同一健康”理念，对基隆博社区居民及其宠物狗这两类脆弱人群进行血支原体检测的研究，且在人类和伴侣动物中均检测到了犬血支原体。
Zotero 插件