Seyama Yusuke, Sugaya Akinori, Koyama Ken, Honda Hiroyuki, Ishibashi Hajime, Yamaoka Masaharu, Ozeki Mitsuharu, Goto Mitsuhide, Araki Masahiro, Amagai Kenji
Department of Gastroenterology Ibaraki Prefectural Central Hospital Ibaraki Japan.
Department of Medical Oncology Ibaraki Prefectural Central Hospital Ibaraki Japan.
DEN Open. 2025 Apr 29;6(1):e70130. doi: 10.1002/deo2.70130. eCollection 2026 Apr.
Hemobilia, or hemorrhage within the biliary system, is an uncommon cause of stent obstruction associated with bile duct strictures that are rarely observed with plastic stents. Reports of a pseudoaneurysm as a cause of hemobilia after plastic stent placement are also rare. We present a rare case of hemobilia caused by a pseudoaneurysm that resulted in obstructive cholangitis in a patient who underwent plastic stent placement for bile duct invasion caused by pancreatic cancer. A 78-year-old man with a history of stroke who was using antiplatelet therapy presented with obstructive jaundice caused by locally advanced pancreatic cancer and underwent endoscopic plastic stent placement in the bile duct followed by concurrent chemoradiotherapy. Second-line chemotherapy was administered as the disease progressed; however, he experienced obstructive cholangitis and was admitted to our hospital. Hemobilia was identified as the underlying cause; notably, it was not evident during the initial evaluation and was diagnosed during endoscopic stent replacement. Emergency angiography revealed a pseudoaneurysm of the posterior superior pancreaticoduodenal artery, which was successfully treated using coil embolization. Cholangitis and hemobilia resolved, and the patient was discharged without bleeding recurrence.
胆道出血,即胆道系统内出血,是与胆管狭窄相关的支架阻塞的罕见原因,塑料支架很少出现这种情况。关于假性动脉瘤作为塑料支架置入术后胆道出血原因的报道也很少。我们报告一例罕见的由假性动脉瘤引起的胆道出血病例,该病例导致一名因胰腺癌侵犯胆管而接受塑料支架置入术的患者发生阻塞性胆管炎。一名有中风病史且正在接受抗血小板治疗的78岁男性,因局部晚期胰腺癌出现阻塞性黄疸,接受了胆管内镜塑料支架置入术,随后进行同步放化疗。随着疾病进展,给予二线化疗;然而,他出现了阻塞性胆管炎并入住我院。经查明,胆道出血是根本原因;值得注意的是,在初次评估时并不明显,而是在内镜下更换支架期间被诊断出来。急诊血管造影显示胰十二指肠后上动脉假性动脉瘤,通过弹簧圈栓塞成功治疗。胆管炎和胆道出血得到缓解,患者出院,未再次出血。