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在尼日利亚关爱项目中的iTRAIN:嵌套于正在进行的试验中的虚拟实施研究培训课程

iTRAIN During iCARE Nigeria: Virtual Implementation Research Training Course Nested Within an Ongoing Trial.

作者信息

Kuti Kehinde M, Ahonkhai Aima A, Oladeji Bibilola, Zechariah Sarah, Adirieje Chibueze, Omotosho Temitope, Omigbodun Olayinka, Sam-Agudu Nadia A, Kuhns Lisa M, Garofalo Robert, Taiwo Babafemi, Hirschhorn Lisa R

机构信息

Staff Medical Services Department, University College Hospital, Ibadan, Nigeria.

College of Medicine, University of Ibadan, Infectious Disease Institute, Ibadan, Nigeria.

出版信息

Glob Implement Res Appl. 2025;5(2):213-222. doi: 10.1007/s43477-025-00152-y. Epub 2025 Feb 19.

DOI:10.1007/s43477-025-00152-y
PMID:40309221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12037650/
Abstract

BACKGROUND

HIV clinicians and program implementers in Nigeria have limited implementation research training opportunities. We developed a virtual implementation research training program (iTRAIN) for clinicians and HIV program staff implementing the Intensive Combination Approach to Roll Back the Epidemic in Nigerian Adolescents () study.

METHODS

iTRAIN was developed and facilitated by iCARE Nigeria investigators from Nigeria and the United States with extensive implementation research experience. The nine-session online course covered core principles of implementation research. incorporating developing a relevant concept note embedded into iCARE. Between September 2021-2022, content was delivered through asynchronous pre-recorded lectures and readings, followed by facilitator-led synchronous sessions. All six study site teams were assigned a course facilitator for mentoring to develop implementation research proposals nested in the iCARE study. We conducted pre- and post-training surveys to evaluate iTRAIN using the Kirkpatrick Framework and conducted analysis using explanatory mixed methods.

FINDINGS

We enrolled 42 participants (55% male, 48% clinicians), with 50% of enrollees reporting no IR experience. Completion rate was 95%; 79% of participants rated the course overall as "excellent", and 79% reported that their goal of gaining implementation research knowledge were met "a lot". IR knowledge increased "a lot" in 71%, and 97% would "probably or definitely" use their iTRAIN knowledge in future research. All six sites developed implementation research concept notes addressing topics relevant to iCARE Nigeria, with four implemented.

CONCLUSION

iTRAIN represents a successful embedded implementation research virtual training and mentoring program which resulted in increased participant knowledge and capacity. Our training model can serve as a blueprint for study-embedded implementation research capacity-building in Nigeria and similar settings.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s43477-025-00152-y.

摘要

背景

尼日利亚的艾滋病临床医生和项目实施人员接受实施研究培训的机会有限。我们为参与“在尼日利亚青少年中采用强化综合方法抗击艾滋病流行”()研究的临床医生和艾滋病项目工作人员开发了一个虚拟实施研究培训项目(iTRAIN)。

方法

iTRAIN由来自尼日利亚和美国的iCARE尼日利亚研究人员开发并提供支持,他们拥有丰富的实施研究经验。这个为期九节的在线课程涵盖了实施研究的核心原则,包括制定嵌入iCARE的相关概念说明。在2021年9月至2022年期间,通过异步预录制讲座和阅读材料提供课程内容,随后是由主持人引导的同步课程。所有六个研究地点的团队都被分配了一名课程主持人进行指导,以制定嵌入iCARE研究的实施研究提案。我们使用柯克帕特里克框架进行了培训前和培训后的调查,以评估iTRAIN,并使用解释性混合方法进行分析。

结果

我们招募了42名参与者(55%为男性,48%为临床医生),50%的参与者表示没有实施研究经验。完成率为95%;79%的参与者对课程总体评价为“优秀”,79%的参与者表示他们获得实施研究知识的目标“很大程度上”得到了满足。71%的参与者的实施研究知识“大幅”增加,97%的参与者“可能或肯定”会在未来的研究中使用他们在iTRAIN中学到的知识。所有六个地点都制定了与尼日利亚iCARE相关主题的实施研究概念说明,其中四个已实施。

结论

iTRAIN是一个成功的嵌入式实施研究虚拟培训和指导项目,提高了参与者的知识和能力。我们的培训模式可以作为尼日利亚及类似环境中基于研究的实施研究能力建设的蓝图。

补充信息

在线版本包含可在10.1007/s43477-025-00152-y获取的补充材料。

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本文引用的文献

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A randomized stepped wedge trial of an intensive combination approach to roll back the HIV epidemic in Nigerian adolescents: iCARE Nigeria treatment support protocol.一项在尼日利亚青少年中逆转艾滋病毒流行的强化联合方法的随机阶梯式楔形试验:iCARE 尼日利亚治疗支持方案。
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Glob Implement Res Appl. 2022;2(4):340-349. doi: 10.1007/s43477-022-00067-y. Epub 2022 Nov 14.
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Past and current status of adolescents living with HIV in South Africa, 2005-2017.南非感染艾滋病毒的青少年的过去和现状,2005-2017 年。
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Building capacity in dissemination and implementation science: a systematic review of the academic literature on teaching and training initiatives.建设传播与实施科学能力:关于教学和培训计划的学术文献的系统综述。
Implement Sci. 2020 Oct 30;15(1):97. doi: 10.1186/s13012-020-01051-6.
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High Medication Possession Ratios Associated With Greater Risk of Virologic Failure Among Youth Compared With Adults in a Nigerian Cohort.尼日利亚队列研究中,与成年人相比,青少年较高的药物持有率与更高的病毒学失败风险相关。
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