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南非感染艾滋病毒的青少年的过去和现状,2005-2017 年。

Past and current status of adolescents living with HIV in South Africa, 2005-2017.

机构信息

Centre for Community Based Research, Human and Social Capabilities Division, Human Sciences Research Council, Durban, South Africa.

Health and Well-Being, Human and Social Capabilities Division, Human Sciences Research Council, Pretoria, South Africa.

出版信息

BMC Res Notes. 2022 Apr 9;15(1):132. doi: 10.1186/s13104-022-06006-2.

DOI:10.1186/s13104-022-06006-2
PMID:35397603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8994368/
Abstract

OBJECTIVES

This paper reports HIV prevalence, incidence, progress towards the UNAIDS (90-90-90) targets, and HIV drug resistance among adolescents living with HIV in South Africa. We conducted secondary analyses using data extracted from the South African national HIV prevalence surveys (2005-2017). Analyses were stratified by sex and age (10-14 and 15-19-years), presenting weighted descriptive statistics, and realised totals.

RESULTS

HIV prevalence increased from 3.0% in 2012 to 3.7% in 2017, translating to 360 582 (95% CI 302 021-419 144) HIV positive adolescents in 2017. Female adolescents bear a disproportionate HIV burden of 5.6% prevalence versus 0.7% for males. HIV incidence remained relatively stable. For the UNAIDS 90-90-90 targets, approximately 62.3% of adolescents knew their HIV status, 65.4% of whom were on antiretroviral therapy, and of these 78.1% on antiretroviral therapy had attained viral load suppression. There are knowledge gaps pertaining to the magnitude of perinatal infections and postnatal infections, and socio-behavioural risk factors for HIV transmission among adolescents in South Africa. There is still a need for focussed interventions targeting adolescent (1) gender disparities in HIV risk (2) screening for HIV, (3) sustained access and adherence to antiretroviral therapy and (3) retention in care to maintain viral load suppression.

摘要

目的

本文报告了南非感染艾滋病毒的青少年中的艾滋病毒流行率、发病率、实现艾滋病规划署(UNAIDS)“90-90-90”目标的进展情况,以及艾滋病毒耐药性。我们使用从南非国家艾滋病毒流行率调查(2005-2017 年)中提取的数据进行了二次分析。分析按性别和年龄(10-14 岁和 15-19 岁)分层,呈现加权描述性统计数据和实际总数。

结果

艾滋病毒流行率从 2012 年的 3.0%上升到 2017 年的 3.7%,这意味着 2017 年有 360582 名(95%CI 302021-419144)艾滋病毒阳性青少年。少女感染艾滋病毒的比例不成比例,流行率为 5.6%,而男孩为 0.7%。艾滋病毒发病率保持相对稳定。在实现艾滋病规划署 90-90-90 目标方面,约有 62.3%的青少年了解自己的艾滋病毒状况,其中 65.4%正在接受抗逆转录病毒治疗,在这些接受治疗的人中,有 78.1%的人达到了病毒载量抑制。南非青少年围产期感染和产后感染的严重程度以及艾滋病毒传播的社会行为风险因素方面仍存在知识差距。仍需要有针对性的干预措施,针对青少年(1)艾滋病毒风险方面的性别差异,(2)艾滋病毒筛查,(3)持续获得和坚持接受抗逆转录病毒治疗,(3)在护理中保持病毒载量抑制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b24/8994368/0d1f0221de58/13104_2022_6006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b24/8994368/b315ca5aab3b/13104_2022_6006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b24/8994368/0d1f0221de58/13104_2022_6006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b24/8994368/b315ca5aab3b/13104_2022_6006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b24/8994368/0d1f0221de58/13104_2022_6006_Fig2_HTML.jpg

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