Sniderman A, Rahal D, Marpole D, Patton R
J Chronic Dis. 1985;38(9):767-74. doi: 10.1016/0021-9681(85)90119-5.
This report tests the hypothesis that, in early diastole, motion of the anterior left atrial wall corresponds to the motion that can be observed in the contiguous posterior wall of the aortic root. To test this hypothesis, we examined the effects of mitral stenosis, exercise in normals, exercise induced left ventricular ischemia, left ventricular hypertrophy and left ventricular dysfunction on this slope. Each altered early diastolic atrioventricular interaction as predicted and therefore, the early diastolic motion of the anterior left atrial wall does appear to be mirrored by the early diastolic slope of the posterior wall of the aortic root. Consequently, if interpreted in the clinical context, measurement of early diastolic slope of the posterior wall of the aortic root may serve as a useful guide to separate patients with severe from those with mild mitral stenosis.
在舒张早期,左心房前壁的运动与主动脉根部相邻后壁可观察到的运动相对应。为验证该假设,我们研究了二尖瓣狭窄、正常人运动、运动诱发的左心室缺血、左心室肥厚及左心室功能障碍对该斜率的影响。每种情况均如预期改变了舒张早期的房室相互作用,因此,左心房前壁的舒张早期运动似乎确实由主动脉根部后壁的舒张早期斜率所反映。因此,若结合临床情况进行解读,测量主动脉根部后壁的舒张早期斜率可能有助于区分重度与轻度二尖瓣狭窄患者。