Li Weiqi, Sewolo Fabrice, Aoun Andrew, Boltena Minyahil Tadesse, Musad Amro, Lindstrand Ann, Alfvén Tobias, Hanson Claudia, El-Khatib Ziad
Department of Global Public Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Field Epidemiology Training Program (FETP), Kinshasa 1004131, Democratic Republic of the Congo.
Children (Basel). 2025 Mar 26;12(4):415. doi: 10.3390/children12040415.
Vaccine preventable diseases remain the leading causes of death among children in Sub-Saharan Africa.
BACKGROUND/OBJECTIVES: As vaccines provide the best possible protection only when all required doses are received, it is essential to understand how the published literature is designed and conducted regarding the completion of recommended childhood vaccine series for children aged 12-23 months in SSA.
A comprehensive search was conducted across five databases (PubMed, Embase, CINAHL, Web of Science, and Google Scholar) to identify the relevant literature published between January 2000 through December 2023.
A total of 53 studies meeting the inclusion criteria were identified from the five databases. Over half of the studies used a cross-sectional design ( = 32, 60.4%), and less than half of the studies were conducted in Ethiopia ( = 23, 43.4%). The prevalence and associated factors of vaccination series completion were the most commonly explored topics in the literature. The most frequently reported factors associated with vaccine series completion included the caregiver's education level, household wealth status, number of children under five in the household, knowledge of immunization, maternal education, place of residence, gender of the household head or decision maker, utilization of antenatal or postnatal care visits, place of delivery, distance to a healthy facility or travel time, and possession of a vaccination card.
This scoping review identified methodological gaps in the published literature, including a lack of publications from many Sub-Saharan Africa countries and insufficient evidence on trends and inequalities in vaccine series completion. Future research on vaccine series completion is recommended to address these gaps.
在撒哈拉以南非洲，疫苗可预防疾病仍是儿童死亡的主要原因。
背景/目的：由于疫苗只有在接种所有规定剂量后才能提供最佳保护，因此了解已发表的关于撒哈拉以南非洲12至23个月儿童完成推荐儿童疫苗接种系列的文献是如何设计和开展的至关重要。
在五个数据库（PubMed、Embase、CINAHL、科学网和谷歌学术）中进行了全面搜索，以确定2000年1月至2023年12月期间发表的相关文献。
从这五个数据库中总共确定了53项符合纳入标准的研究。超过一半的研究采用横断面设计（n = 32，60.4%），不到一半的研究在埃塞俄比亚进行（n = 23，43.4%）。疫苗接种系列完成率及其相关因素是文献中最常探讨的主题。与疫苗接种系列完成最常报告的相关因素包括照顾者的教育水平、家庭财富状况、家庭中五岁以下儿童的数量、免疫知识、母亲教育程度、居住地点、户主或决策者的性别、产前或产后护理就诊的利用情况、分娩地点、到医疗机构的距离或出行时间以及是否拥有疫苗接种卡。
这项范围综述确定了已发表文献中的方法学差距，包括撒哈拉以南非洲许多国家缺乏相关出版物，以及关于疫苗接种系列完成趋势和不平等问题的证据不足。建议未来针对疫苗接种系列完成情况开展研究以弥补这些差距。
