Liu Xian, Wen Shuang, Wu Dandan
Department of Nursing, Jinzhou Medical University, No.40, Section 3, Songpo Road, Linghe District, Jinzhou City, 121001, Liaoning Province, China.
Department of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Renmin Street, No.2, Guta District, Jinzhou City, 121000, Liaoning Province, China.
Sci Rep. 2025 May 1;15(1):15312. doi: 10.1038/s41598-025-99852-6.
To investigate the mediating role of family care and self-efficacy between stigma and social alienation among colorectal cancer survivors. In a cross-sectional study, 357 colorectal cancer survivors were recruited in northern China. The General Alienation Scale, Social Impact Scale, Family Care Index Questionnaire, and General Self-efficacy Scale were used to conduct the survey, and the mediation model was constructed and tested. Data were statistically analyzed using SPSS 25.0 software. Colorectal cancer survivors' social alienation was positively correlated with stigma (r = .481), and negatively correlated with family care (r = -.514)、and self-efficacy (r = -.506). Family care and self-efficacy both partially mediated the relationship between stigma and social alienation, with mediator effect values of 0.10 and 0.12, and the two consecutive paths were chained together, with a mediator effect of 0.02. Colorectal cancer survivors' stigma and social alienation are at a moderate level, and the stigma can directly and indirectly contribute to social alienation through family care and self-efficacy. Healthcare professionals can take targeted interventions to improve patients' family care and self-efficacy and reduce their social alienation, to promote the social integration of colorectal cancer survivors and improve the quality of life.
探讨家庭关怀和自我效能感在结直肠癌幸存者耻辱感与社会疏离感之间的中介作用。在一项横断面研究中，在中国北方招募了357名结直肠癌幸存者。使用一般疏离感量表、社会影响量表、家庭关怀指数问卷和一般自我效能量表进行调查，并构建和检验中介模型。使用SPSS 25.0软件对数据进行统计分析。结直肠癌幸存者的社会疏离感与耻辱感呈正相关（r = 0.481），与家庭关怀呈负相关（r = -0.514）以及与自我效能感呈负相关（r = -0.506）。家庭关怀和自我效能感均部分中介了耻辱感与社会疏离感之间的关系，中介效应值分别为0.10和0.12，且两条连续路径相互连锁，中介效应为0.02。结直肠癌幸存者的耻辱感和社会疏离感处于中等水平，耻辱感可通过家庭关怀和自我效能感直接和间接导致社会疏离感。医护人员可采取针对性干预措施，改善患者的家庭关怀和自我效能感，减少其社会疏离感，以促进结直肠癌幸存者的社会融入并提高生活质量。
