Lv Meng, Li Ying, Guo Zihan, Ma Lu, Zhang Lei
China-Australia Joint Research Center for Infectious Diseases, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Obesity (Silver Spring). 2025 Jun;33(6):1195-1206. doi: 10.1002/oby.24296. Epub 2025 May 1.
This study aimed to examine the bidirectional associations between indicators of adiposity and mental health.
Using longitudinal data from 60,319 UK Biobank participants, we explored the bidirectional associations between mental health (including neuroticism, recent depressive symptoms, probable depression status, stress, mania, life satisfaction, and happiness) and adiposity indicators (including BMI, waist circumference, body fat percentage, and different obesity types).
The multivariate logistic regressions and mixed-effects models revealed the following: 1) BMI and general obesity were bidirectionally associated with recent depressive symptoms, having probable depression status, experiencing at least one type of stress (especially stress from serious illness, injury, or assault to oneself or financial difficulties), and life satisfaction (especially health satisfaction and financial situation satisfaction); 2) waist circumference and abdominal obesity were bidirectionally associated with recent depressive symptoms and financial situation satisfaction; and 3) body fat percentage and high body fat percentage were bidirectionally associated with recent depressive symptoms, experiencing stress from financial difficulties, health satisfaction, and financial situation satisfaction.
The bidirectional associations between specific indicators of adiposity and mental health depend on the types of adiposity.
本研究旨在探讨肥胖指标与心理健康之间的双向关联。
利用来自60319名英国生物银行参与者的纵向数据，我们探究了心理健康（包括神经质、近期抑郁症状、可能的抑郁状态、压力、躁狂、生活满意度和幸福感）与肥胖指标（包括体重指数、腰围、体脂百分比和不同类型的肥胖）之间的双向关联。
多变量逻辑回归和混合效应模型显示如下结果：1）体重指数和一般肥胖与近期抑郁症状、处于可能的抑郁状态、经历至少一种压力（特别是来自严重疾病、伤害、对自己的攻击或经济困难的压力）以及生活满意度（特别是健康满意度和财务状况满意度）存在双向关联；2）腰围和腹部肥胖与近期抑郁症状和财务状况满意度存在双向关联；3）体脂百分比和高体脂百分比与近期抑郁症状、经历经济困难带来的压力、健康满意度和财务状况满意度存在双向关联。
肥胖的特定指标与心理健康之间的双向关联取决于肥胖的类型。
