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草药凝胶作为III期牙周炎非手术牙周治疗辅助手段的比较评价:一项随机分口临床试验。

Comparative evaluation of herbal gel as an adjunct to nonsurgical periodontal therapy in Stage III periodontitis: A randomized split-mouth clinical trial.

作者信息

Rathod Surekha Ramrao, Kaule Supriya Suresh, Bawankar Pranjali Vijaykumar, Kolte Abhay Pandurang

机构信息

Departments of Periodontics and Implant Dentistry, Ranjeet Deshmukh Dental College and Research Centre, Nagpur, Maharashtra, India.

出版信息

J Indian Soc Periodontol. 2024 Nov-Dec;28(6):638-642. doi: 10.4103/jisp.jisp_346_23. Epub 2025 Apr 3.

Abstract

BACKGROUND AND OBJECTIVES

Many Ayurvedic and herbal medications are used to overcome the drawbacks of allopathic medications. The objective of the current study was to assess and contrast the osteoanabolic effects of Picrorhiza kurroa and F. bengalensis gel on the quantity of bone fill in Stage III periodontitis using Radiovisiography (RVG).

MATERIALS AND METHODS

In the present split-mouth trial, 44 bilateral intrabony defects (IBDs) were randomly assigned to two groups. Group I received nonsurgical periodontal therapy (NSPT) alone, whereas Group II received NSPT along with Picrorhiza Kurroa and Ficus Bengalensis gel. The IBD fill using RVG was the primary outcome measurement and secondary outcomes were probing pocket depth, clinical attachment level, plaque index, and modified sulcus bleeding index reported at baseline, 3 months, and 6 months.

RESULTS

Both the study groups exhibited improvements in the measurements that were evaluated, although Group II significantly outperformed Group I in terms of IBD fill and clinical parameters.

CONCLUSION

As a supplement to NSPT, the use of picrorhiza kurroa and ficus bengalensis gel is more advantageous in obtaining superior clinical and radiographic outcomes after 3 and 6 months.

摘要

背景与目的

许多阿育吠陀药物和草药被用于克服对抗疗法药物的缺点。本研究的目的是使用放射成像(RVG)评估并对比胡黄连和孟加拉榕凝胶对III期牙周炎骨填充量的骨合成代谢作用。

材料与方法

在本次双侧对照试验中,44个双侧骨内缺损(IBD)被随机分为两组。第一组仅接受非手术牙周治疗(NSPT),而第二组在接受NSPT的同时还使用胡黄连和孟加拉榕凝胶。使用RVG测量IBD填充情况是主要结局指标,次要结局指标为基线、3个月和6个月时报告的探诊袋深度、临床附着水平、菌斑指数和改良龈沟出血指数。

结果

两个研究组在各项评估指标上均有改善,尽管在IBD填充和临床参数方面,第二组显著优于第一组。

结论

作为NSPT的补充,使用胡黄连和孟加拉榕凝胶在3个月和6个月后获得更好的临床和影像学结果方面更具优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1452/12043210/67ca4b6e30ee/JISP-28-638-g001.jpg

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