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通过脑脊液靶向新一代测序检测到的神经囊尾蚴病:一例报告

Neurocysticercosis detected by targeted next-generation sequencing of cerebrospinal fluid: a case report.

作者信息

Ren Xintong, Sun HuiQin, Cheng Yanghong, Zhang Yunzhou, Gao Daiquan

机构信息

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Department of Neurology, The Fifth People's Hospital of Huai'an and the Affiliated Huai'an Hospital of Yangzhou University, Huai'an, China.

出版信息

Front Neurol. 2025 Apr 17;16:1504348. doi: 10.3389/fneur.2025.1504348. eCollection 2025.

Abstract

The patient, a middle-aged male with a long history of the disease, had experienced recurrent headaches for 26 years and episodic shaking of the right limb with slurred speech for the past month. He was previously diagnosed with cerebral cysticercosis and had shown improvement after anthelmintic treatment. In recent years, he noted a resurgence of headaches. One month prior, he developed right limb shaking and occasional slurred speech. A clinical neurological examination was unremarkable, but cranial MRI and cerebrospinal fluid sequencing confirmed a diagnosis of cerebral cysticercosis. Anthelmintic treatment was administered, resulting in symptom improvement.

摘要

该患者为中年男性,病史较长,26年来反复头痛,近1个月出现右肢阵发震颤伴言语不清。既往诊断为脑囊尾蚴病,驱虫治疗后症状曾有改善。近年来,他注意到头痛复发。1个月前,他出现右肢震颤及偶尔言语不清。临床神经学检查未见异常,但头颅磁共振成像(MRI)及脑脊液测序确诊为脑囊尾蚴病。给予驱虫治疗后,症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80d5/12043463/bbb40f34eb91/fneur-16-1504348-g001.jpg

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