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Key advances and application prospects of PROTAC technologies in the next 5 years.

作者信息

Qin Shuanglin, Xiao Xiaohe

机构信息

Senior Department of Hepatology, China Military Institute of Chinese Materia, The Fifth Medical Center of PLA General Hospital, Beijing, P.R. China.

National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Research Center for Precision Medication of Chinese Medicine, FuRong Laboratory, Hunan University of Chinese Medicine, Changsha, P.R. China.

出版信息

Future Med Chem. 2025 May;17(9):987-989. doi: 10.1080/17568919.2025.2498875. Epub 2025 May 2.

Abstract
摘要

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本文引用的文献

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PROTACs coupled with oligonucleotides to tackle the undruggable.与寡核苷酸偶联的PROTAC用于攻克不可成药靶点。
Bioanalysis. 2025 Feb;17(4):261-276. doi: 10.1080/17576180.2025.2459528. Epub 2025 Feb 3.
2
PROTACs in the treatment of viral diseases.用于治疗病毒性疾病的蛋白水解靶向嵌合体(PROTACs)
Future Med Chem. 2025 Feb;17(3):267-269. doi: 10.1080/17568919.2025.2453418. Epub 2025 Jan 15.
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Nano-PROTACs: state of the art and perspectives.纳米-PROTACs:现状与展望。
Nanoscale. 2024 Feb 29;16(9):4378-4391. doi: 10.1039/d3nr06059d.

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