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锡兰钩虫(Ancylostoma ceylanicum,(卢斯,1911年))在金黄仓鼠(Mesocricetus auratus)中的致病性及对初次感染的体液免疫反应

Ancylostoma ceylanicum (Looss, 1911) in golden hamsters (Mesocricetus auratus): pathogenicity and humoral immune response to a primary infection.

作者信息

Menon S, Bhopale M K

出版信息

J Helminthol. 1985 Jun;59(2):143-6. doi: 10.1017/s0022149x00025724.

DOI:10.1017/s0022149x00025724
PMID:4031453
Abstract

The response of hamsters to Ancylostoma ceylanicum was studied between days 13 and 200 after infection. The infected hamsters showed signs of anaemia, particularly between the 13th and 60th days. A significant loss in body-weight in the infected animals was also observed during this period. Serological studies with agar gel-diffusion, counterimmunoelectrophoresis and indirect haemagglutination tests revealed positive reactions between the 20th and 60th days followed by a negative response in the latent period between the 60th and 200th days of infection, counterimmunoelectrophoresis test remained positive for a period of 150 days in this experimental model.

摘要

在感染后的第13天至200天期间,对仓鼠感染锡兰钩虫的反应进行了研究。受感染的仓鼠出现贫血症状,尤其是在第13天至60天之间。在此期间,还观察到受感染动物体重显著下降。采用琼脂凝胶扩散、对流免疫电泳和间接血凝试验进行的血清学研究显示,在第20天至60天之间出现阳性反应,随后在感染后第60天至200天的潜伏期出现阴性反应,在该实验模型中,对流免疫电泳试验在150天内保持阳性。

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Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster.
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Oral transfer of adult Ancylostoma ceylanicum hookworms into permissive and nonpermissive host species.将成年锡兰钩虫经口转移至易感和非易感宿主物种。
Infect Immun. 2003 Apr;71(4):1880-6. doi: 10.1128/IAI.71.4.1880-1886.2003.